Application of a forward model of axisymmetric shear wave propagation in viscoelastic media to shear wave elastography

被引:4
|
作者
Yengul, Sanjay S. [1 ,2 ]
Barbone, Paul E. [1 ]
Madore, Bruno [2 ]
机构
[1] Boston Univ, Mech Engn, 110 Cummington Mall, Boston, MA 02215 USA
[2] Harvard Med Sch, Dept Radiol, Brigham & Womens Hosp, 75 Francis St, Boston, MA 02115 USA
来源
基金
美国国家卫生研究院; 美国国家科学基金会;
关键词
ELASTIC PROPERTIES; PHANTOM; QUANTIFICATION; DISPERSION; FIBROSIS; TISSUE;
D O I
10.1121/1.5038568
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
A simple but general solution of Navier's equation for axisymmetric shear wave propagation in a homogeneous isotropic viscoelastic medium is presented. It is well-suited for use as a forward model for some acoustic radiation force impulse based shear wave elastography applications because it does not require precise knowledge of the strength of the source, nor its spatial or temporal distribution. Instead, it depends on two assumptions: (1) the source distribution is axisymmetric and confined to a small region near the axis of symmetry, and (2) the propagation medium is isotropic and homogeneous. The model accounts for the vector polarization of shear waves and exactly represents geometric spreading of the shear wavefield, whether spherical, cylindrical, or neither. It makes no assumption about the frequency dependence of material parameters, i.e., it is material-model independent. Validation using measured shear wavefields excited by acoustic radiation force in a homogeneous gelatin sample show that the model accounts for well over 90% of the measured wavefield "energy." An optimal fit of the model to simulated shear wavefields with noise in a homogeneous viscoelastic medium enables estimation of both the shear storage modulus and shear wave attenuation to within 1%. (C) 2018 Acoustical Society of America.
引用
收藏
页码:3266 / 3277
页数:12
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