Transgenic Mouse Models of SV40-Induced Cancer

被引：11

作者：

Hudson, Amanda L. ^{[1
]}

Colvin, Emily K. ^{[1
]}

机构：

[1] Univ Sydney, Bill Walsh Translat Canc Res Lab, Sydney Med Sch Northern, Kolling Inst,Northern Sydney Local Hlth Dist, St Leonards, NSW, Australia

来源：

ILAR JOURNAL | 2016年 / 57卷 / 01期

关键词：

cancer; mouse model; SV40; transgenic; SIMIAN-VIRUS-40; T-ANTIGEN; LARGE TUMOR-ANTIGEN; VILLUS-ASSOCIATED ENTEROCYTES; TRANSITIONAL-CELL CARCINOMA; GROWTH-FACTOR RECEPTOR; HEPATOCELLULAR-CARCINOMA; MAMMARY-CANCER; IN-SITU; REGULATORY ELEMENTS; INTRAOCULAR TUMORS;

D O I：

10.1093/ilar/ilw001

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The SV40 viral oncogene has been used since the 1970s as a reliable and reproducible method to generate transgenic mouse models. This seminal discovery has taught us an immense amount about how tumorigenesis occurs, and its success has led to the evolution of many mouse models of cancer. Despite the development of more modern and targeted approaches for developing genetically engineered mouse models of cancer, SV40-induced mouse models still remain frequently used today. This review discusses a number of cancer types in which SV40 mouse models of cancer have been developed and highlights their relevance and importance to preclinical research.

引用

页码：44 / 54

页数：11

共 50 条

[1] SV40-INDUCED T-ANTIGEN IN MOUSE CELLS
FISCHER, H
FEBS LETTERS, 1974, 43 (02) : 219 - 222
[2] THE IMMUNOPATHOLOGY OF SV40-INDUCED TRANSFORMATION
MORA, PT
SPRINGER SEMINARS IN IMMUNOPATHOLOGY, 1982, 5 (01): : 7 - 32
[3] SV40-INDUCED TRANSFORMATION - THE CELLULAR PROTEIN P53 APPEARS TO BE A SUBSTRATE FOR AN SV40-INDUCED PROTEIN-KINASE
SCHEIDTMANN, KH
ZENTRALBLATT FUR BAKTERIOLOGIE MIKROBIOLOGIE UND HYGIENE SERIES A-MEDICAL MICROBIOLOGY INFECTIOUS DISEASES VIROLOGY PARASITOLOGY, 1988, 268 (01): : 121 - 121
[4] STUDIES OF PREVENTION OF SV40-INDUCED TUMORS IN HAMSTERS
GIRARDI, AJ
TRANSPLANTATION, 1968, 6 (04) : 643 - &
[5] IMMUNE CONTROL OF SV40-INDUCED TUMORS IN MICE
PAN, S
ABRAMCZUK, J
KNOWLES, BB
INTERNATIONAL JOURNAL OF CANCER, 1987, 39 (06) : 722 - 728
[6] ANTIGENIC STUDY OF UNFERTILIZED MOUSE EGGS - CROSS REACTIVITY WITH SV40-INDUCED ANTIGENS
BARANSKA, W
KOLDOVSKY, P
KOPROWSKI, H
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1970, 67 (01) : 193 - +
[7] SV40-INDUCED IMMORTALIZATION OF HUMAN-CELLS
BRYAN, TM
REDDEL, RR
CRITICAL REVIEWS IN ONCOGENESIS, 1994, 5 (04): : 331 - 357
[8] NON-COORDINATE EXPRESSION OF SV40-INDUCED TRANSFORMATION AND TUMORIGENICITY IN MOUSE CELL HYBRIDS
HOWELL, N
SAGER, R
SOMATIC CELL GENETICS, 1979, 5 (01): : 129 - 143
[9] AN SV40-INDUCED TRANSCRIPTION FACTOR ACTIVATING THE LATE PROMOTER
BEARD, P
BRUGGMANN, H
EXPERIENTIA, 1987, 43 (06): : 681 - 681
[10] SV40 TAg mouse models of cancer
Colvin, Emily K.
Weir, Chris
Ikin, Rowan J.
Hudson, Amanda L.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 2014, 27 : 61 - 73

← 1 2 3 4 5 →