Central Nervous System Involvement of T-cell Prolymphocytic Leukemia Diagnosed with Stereotactic Brain Biopsy: Case Report

被引：4

作者：

Gocmen, Selcuk ^{[1
]}

Kutlay, Murat ^{[2
]}

Erikci, Alev ^{[3
]}

Atabey, Cem ^{[1
]}

Sayan, Ozkan ^{[3
]}

Haholu, Aptullah ^{[4
]}

机构：

[1] Gulhane Mil Med Acad, Haydarpasa Training Hosp, Dept Neurosurg, Istanbul, Turkey

[2] Gulhane Mil Med Acad, Dept Neurosurg, Ankara, Turkey

[3] Gulhane Mil Med Acad, Haydarpasa Training Hosp, Dept Hematol, Istanbul, Turkey

[4] Gulhane Mil Med Acad, Haydarpasa Training Hosp, Dept Pathol, Istanbul, Turkey

来源：

TURKISH JOURNAL OF HEMATOLOGY | 2014年 / 31卷 / 01期

关键词：

T-cell prolymphocytic leukemia; Cerebral involvement; Central nervous system; Stereotactic biopsy; CHRONIC LYMPHOCYTIC-LEUKEMIA; MENINGEAL INVOLVEMENT;

D O I：

10.4274/Tjh.2012.0028

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Prolymphocytic leukemia (PLL) is a generalized malignancy of the lymphoid tissue characterized by the accumulation of monoclonal lymphocytes, usually of B cell type. Involvement of the central nervous system (CNS) is an extremely rare complication of T-cell prolymphocytic leukemia (T-PLL). We describe a case of T-PLL presenting with symptomatic infiltration of the brain that was histopathologically proven by stereotactic brain biopsy. We emphasize the importance of rapid diagnosis and immediate treatment for patients presenting with CNS involvement and a history of leukemia or lymphoma.

引用

页码：75 / 78

页数：4

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