Differential expression of genes linked to the leukemia inhibitor factor signaling pathway during the estrus cycle and early pregnancy in the porcine endometrium
The objective of this study was to determine the expression profiles of leukemia inhibitory factor (LIF) and its receptor (LIFR), interleukin 6 receptor (IL6R), tumor protein p53 (TP53) and B-cell CLL/lymphoma 2 (BCL2) in the porcine endometrium on selected days of the estrous cycle and pregnancy. Time- and reproductive status (estrous cycle/pregnancy)-specific patterns of expression were identified for all investigated genes. The most pronounced changes were seen on Days 12 and 14 of pregnancy when maternal recognition of pregnancy and implantation, respectively, occurs in pigs. (C) 2014 Society for Biology of Reproduction & the Institute of Animal Reproduction and Food Research of Polish Academy of Sciences in Olsztyn. Published by Elsevier Urban & Partner Sp. z o.o. All rights reserved.
机构:
Dicle Univ, Dept OBGYN, Fac Vet Med, TR-21280 Diyarbakir, Turkey
Selcuk Univ, Fac Vet Med, Dept OBGYN, TR-42031 Konya, TurkeyDicle Univ, Dept OBGYN, Fac Vet Med, TR-21280 Diyarbakir, Turkey
Atli, Mehmet Osman
Guzeloglu, Aydin
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Selcuk Univ, Fac Vet Med, Dept OBGYN, TR-42031 Konya, TurkeyDicle Univ, Dept OBGYN, Fac Vet Med, TR-21280 Diyarbakir, Turkey
Guzeloglu, Aydin
Dinc, Dursun Ali
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Selcuk Univ, Fac Vet Med, Dept OBGYN, TR-42031 Konya, TurkeyDicle Univ, Dept OBGYN, Fac Vet Med, TR-21280 Diyarbakir, Turkey