Monitoring laser treatment of port wine stains using phase-resolved optical Doppler tomography

被引：3
|
作者：
Zhao, YH [1 ]
Chen, ZP [1 ]
Saxer, CE [1 ]
de Boer, JF [1 ]
Majaron, B [1 ]
Verkruysse, W [1 ]
Nelson, JS [1 ]
机构：
[1] Univ Calif Irvine, Beckman Laser Inst & Med Clin, Irvine, CA 92612 USA
来源：
COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICAL SCIENCE AND CLINICAL APPLICATIONS IV | 2000年 / 3915卷
关键词：
ODT; OCT; Hilbert transform; phase-resolved ODT; PWS; laser therapy;
D O I：
10.1117/12.384162
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
We used a novel phase-resolved optical Doppler tomographic (ODT) technique, with very high flow velocity sensitivity (10 mu m/s) and high spatial resolution (10 mu m), to image blood flow in port wine stain (PWS) birthmarks in human skin. The variance of blood flow velocity is used to locate the PWS vessels in addition to the regular ODT images. Our device combines an ODT system and laser so that PWS blood flow can be monitored in situ before and after treatment. To our knowledge, this is the first clinical application of ODT to provide a fast semi-quantitative evaluation of the efficacy of PWS laser therapy in situ and in real-time.
引用
收藏
页码：237 / 242
页数：6
相关论文
共 50 条
  • [1] Phase-resolved frequency domain optical Doppler tomography
    Wang, L
    Wang, Y
    Bachman, M
    Li, GP
    Chen, ZP
    COHERENCE DOMAIN OPTICAL METHODS AND OPTICAL COHERENCE TOMOGRAPHY IN BIOMEDICINE VIII, 2004, 5316 : 432 - 438
  • [2] Frequency domain phase-resolved optical Doppler and Doppler variance tomography
    Wang, L
    Wang, YM
    Guo, SG
    Zhang, J
    Bachman, M
    Li, GP
    Chen, ZP
    OPTICS COMMUNICATIONS, 2004, 242 (4-6) : 345 - 350
  • [3] Imaging and quantifying of microflow by phase-resolved optical Doppler tomography
    Wang, L
    Xu, W
    Bachman, M
    Li, GP
    Chen, ZP
    MICROFLUIDICS, BIOMEMS, AND MEDICAL MICROSYSTEMS II, 2004, 5345 : 214 - 219
  • [4] Phase-resolved Doppler optical coherence tomography - limitations and improvements
    Szkulmowska, Anna
    Szkulmowski, Maciej
    Kowalczyk, Andrzej
    Wojtkowski, Maciej
    OPTICS LETTERS, 2008, 33 (13) : 1425 - 1427
  • [5] Imaging and quantifying of microflow by phase-resolved optical Doppler tomography
    Wang, L
    Xu, W
    Bachman, M
    Li, GP
    Chen, ZP
    OPTICS COMMUNICATIONS, 2004, 232 (1-6) : 25 - 29
  • [6] LASER TREATMENT OF PORT WINE STAINS
    CARRUTH, JAS
    BRITISH MEDICAL JOURNAL, 1982, 284 (6323): : 1195 - 1195
  • [7] LASER TREATMENT OF PORT WINE STAINS
    SHEEHANDARE, RA
    BRITISH MEDICAL JOURNAL, 1993, 306 (6874): : 394 - 395
  • [8] Laser treatment of port wine stains
    不详
    OPTICS AND LASER TECHNOLOGY, 1997, 29 (03): : R3 - R3
  • [9] LASER TREATMENT OF PORT WINE STAINS
    DAVE, VK
    BRITISH MEDICAL JOURNAL, 1982, 285 (6336): : 215 - 215
  • [10] LASER TREATMENT OF PORT WINE STAINS
    LANDTHALER, M
    BRAUNFALCO, O
    HAINA, D
    WAIDELICH, W
    DERMATOLOGICA, 1987, 175 (03): : 156 - 160
12345