Chiral β-amino sulfoxides as chiral ligands in palladium-catalyzed asymmetric allylations

被引：23
|
作者：
Hiroi, K [1 ]
Suzuki, Y [1 ]
机构：
[1] Tohoku Coll Pharm, Dept Synthet Organ Chem, Aoba Ku, Sendai, Miyagi 981, Japan
来源：
HETEROCYCLES | 1997年 / 46卷
关键词：
D O I：
10.3987/COM-97-S27
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
New chiral p-amino sulfoxide ligands bearing chiral sulfinyl functionality as a sole chiral source have been deviced and palladium-catalyzed asymmetric allylations of acetoacetate with these ligands have been examined. The highest enantioselectivity (50%) was observed with 5b. The participation of chiral sulfinyl functionality to palladium catalysts is discussed on the basis of the stereochemical outcome obtained.
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页码：77 / 81
页数：5
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