Angiotensin II Activates P25/CDK5 Pathway and Regulates SIRT1 Signaling in Endothelial Cells

被引:0
|
作者
Singh, Sandeep [1 ]
Mondaca-Ruff, David [1 ]
Konja, Daniels [1 ]
Kim, Ji Yong [1 ]
Chlopicki, Stefan [2 ]
Wang, Yu [1 ]
机构
[1] Univ Hong Kong, Dept Pharmacol & Pharm, Hong Kong, Peoples R China
[2] Jagiellonian Univ, Jagiellonian Ctr Expt Therapeut JCET, Krakow, Poland
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
PS03
引用
收藏
页码:98 / 98
页数:1
相关论文
共 50 条
  • [21] Cdk5/p25 inhibitory peptide (CIP) derived from p35 regulates Tau protein phosphorylation in transfected cells
    Zheng, YL
    Li, BS
    Amin, ND
    Pant, HC
    MOLECULAR BIOLOGY OF THE CELL, 2001, 12 : 11A - 11A
  • [22] Identification of Novel Compounds Inhibiting the Kinase Activity of the CDK5/p25 Complex via Direct Binding to p25
    Jabeur, Riheb
    Corbel, Caroline
    Loyer, Pascal
    Le Parc, Annabelle
    Le Grand, Adelaide
    Comte, Arnaud
    Bach, Stephane
    Andre-Leroux, Gwenaelle
    Sire, Olivier
    Ben Mansour, Hedi
    Le Tilly, Veronique
    BIOCHEMISTRY, 2023, 62 (09) : 1452 - 1463
  • [23] A Cdk5-derived peptide inhibits Cdk5/p25 activity and improves neurodegenerative phenotypes
    Pao, Ping-Chieh
    Seo, Jinsoo
    Lee, Audrey
    Kritskiy, Oleg
    Patnaik, Debasis
    Penney, Jay
    Raju, Ravikiran M.
    Geigenmuller, Ute
    Silva, M. Catarina
    Lucente, Diane E.
    Gusella, James F.
    Dickerson, Bradford C.
    Loon, Anjanet
    Yu, Margaret X.
    Bula, Michael
    Yu, Melody
    Haggarty, Stephen J.
    Tsai, Li-Hue
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 120 (16)
  • [24] Ameliorating Alzheimer's-like Pathology by Minocycline via Inhibiting Cdk5/p25 Signaling
    Zhao, Yu
    Wang, Chuanling
    He, Wenbo
    Cai, Zhiyou
    CURRENT NEUROPHARMACOLOGY, 2022, 20 (09) : 1783 - 1792
  • [25] Calpastatin, an endogenous calpain-inhibitor protein, regulates the cleavage of the Cdk5 activator p35 to p25
    Sato, Ko
    Minegishi, Seiji
    Takano, Jiro
    Plattner, Florian
    Saito, Taro
    Asada, Akiko
    Kawahara, Hiroyuki
    Iwata, Nobuhisa
    Saido, Takaomi C.
    Hisanaga, Shin-ichi
    JOURNAL OF NEUROCHEMISTRY, 2011, 117 (03) : 504 - 515
  • [27] Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
    Gentry N. Patrick
    Lawrence Zukerberg
    Margareta Nikolic
    Suzanne de la Monte
    Pieter Dikkes
    Li-Huei Tsai
    Nature, 1999, 402 : 615 - 622
  • [28] Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
    Patrick, GN
    Zukerberg, L
    Nikolic, M
    de la Monte, S
    Dikkes, P
    Tsai, LH
    NATURE, 1999, 402 (6762) : 615 - 622
  • [29] Regulation of amyloid precursor protein (APP) phosphorylation and processing by p35.Cdk5 and p25/Cdk5
    Liu, F
    Su, Y
    Li, BL
    Zhou, Y
    Ryder, J
    Gonzalez-DeWhitt, P
    May, PC
    Ni, BH
    FEBS LETTERS, 2003, 547 (1-3) : 193 - 196
  • [30] Endothelial overexpression of P25 causes premature vascular aging by promoting SIRT1 protein degradation
    Mondaca-Ruff, David
    Konja, Daniels
    Singh, Sandeep
    Fu, Bowen
    Wang, Yu
    FASEB JOURNAL, 2021, 35