Advanced Monte Carlo simulations of emission tomography imaging systems with GATE

被引：93

作者：

Sarrut, David ^{[1
]}

Bala, Mateusz ^{[2
]}

Bardies, Manuel ^{[3
]}

Bert, Julien ^{[4
]}

Chauvin, Maxime ^{[5
]}

Chatzipapas, Konstantinos ^{[6
]}

Dupont, Mathieu ^{[7
]}

Etxebeste, Ane ^{[1
]}

Fanchon, Louise M. ^{[8
]}

Jan, Sebastien ^{[9
]}

Kayal, Gunjan ^{[5
,10
]}

Kirov, Assen S. ^{[8
]}

Kowalski, Pawel ^{[11
]}

Krzemien, Wojciech ^{[11
]}

Labour, Joey ^{[1
]}

Lenz, Mirjam ^{[12
,13
]}

Loudos, George ^{[6
]}

Mehadji, Brahim ^{[7
]}

Menard, Laurent ^{[14
,15
]}

Morel, Christian ^{[7
]}

Papadimitroulas, Panagiotis ^{[6
]}

Rafecas, Magdalena ^{[16
]}

Salvadori, Julien ^{[17
,18
]}

Seiter, Daniel ^{[19
]}

Stockhoff, Mariele ^{[20
]}

Testa, Etienne ^{[21
]}

Trigila, Carlotta ^{[22
]}

Pietrzyk, Uwe ^{[13
]}

Vandenberghe, Stefaan ^{[20
]}

Verdier, Marc-Antoine ^{[14
,15
]}

Visvikis, Dimitris ^{[4
]}

Ziemons, Karl ^{[12
]}

Zvolsky, Milan ^{[16
]}

Roncali, Emilie ^{[22
]}

机构：

[1] Univ Lyon, Univ Lyon 1, Inserm U1294, CNRS UMR5220,INSA Lyon,CREATIS, Lyon, France

[2] Jagiellonian Univ, Krakow, Poland

[3] Montpellier Univ, Canc Res Inst Montpellier, U1194 INSERM, ICM, 208 Av Apothicaires, F-34298 Montpellier 5, France

[4] Univ Brest, Fac Med, IBRBS, LaTIM,INSERM UMR 1101, 22 Ave Camille Desmoulins, F-29238 Brest, France

[5] Univ Toulouse III Paul Sabatier, INSERM, CRCT, UMR 1037, Toulouse, France

[6] Bioemiss Technol Solut BIOEMTECH, Alexandras Av 116, Athens, Greece

[7] Aix Marseille Univ, CPPM, CNRS, IN2P3, Marseille, France

[8] Mem Sloan Kettering Canc Ctr, Dept Med Phys, New York, NY 10065 USA

[9] Univ Paris Saclay, Serv Hosp Frederic Joliot, BioMaps, INSERM,CEA,CNRS, F-91401 Orsay, France

[10] Belgian Nucl Res Ctr, SCK CEN, Boeretang 200, B-2400 Mol, Belgium

[11] Natl Ctr Nucl Res, High Energy Phys Div, Otwock Wierk, Poland

[12] FH Aachen Univ Appl Sci, Forschungszentrum Julich, Julich, Germany

[13] Univ Wuppertal, Fac Math & Nat Sci, Wuppertal, Germany

[14] Univ Paris Saclay, IJCLab, CNRS, IN2P3, F-91405 Orsay, France

[15] Univ Paris, IJCLab, F-91405 Orsay, France

[16] Univ Lubeck, Inst Med Engn, Lubeck, Germany

[17] Univ Lorraine, Dept Nucl Med, CHRU Nancy, F-54000 Nancy, France

[18] Univ Lorraine, Nancyclotep Mol Imaging Platform, CHRU Nancy, F-54000 Nancy, France

[19] Univ Wisconsin, Dept Med Phys, Sch Med & Publ Hlth, Madison, WI 53705 USA

[20] Univ Ghent, Med Image & Signal Proc MEDISIP, Ghent, Belgium

[21] Univ Claude Bernard Lyon 1, Univ Lyon, IP2I Lyon, CNRS,IN2P3, F-69622 Villeurbanne, France

[22] Univ Calif Davis, Dept Biomed Engn, Davis, CA 95616 USA

来源：

PHYSICS IN MEDICINE AND BIOLOGY | 2021年 / 66卷 / 10期

基金：

欧盟地平线“2020”;

关键词：

Monte Carlo simulation; Positron emission tomography; Single-photon emission computed tomography; Compton Camera; MONOLITHIC SCINTILLATOR CRYSTALS; PET SCANNER; NUCLEAR-MEDICINE; GAMMA-CAMERA; NEURAL-NETWORK; VALIDATION; MODEL; DETECTOR; OPTIMIZATION; PERFORMANCE;

D O I：

10.1088/1361-6560/abf276

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Built on top of the Geant4 toolkit, GATE is collaboratively developed for more than 15 years to design Monte Carlo simulations of nuclear-based imaging systems. It is, in particular, used by researchers and industrials to design, optimize, understand and create innovative emission tomography systems. In this paper, we reviewed the recent developments that have been proposed to simulate modern detectors and provide a comprehensive report on imaging systems that have been simulated and evaluated in GATE. Additionally, some methodological developments that are not specific for imaging but that can improve detector modeling and provide computation time gains, such as Variance Reduction Techniques and Artificial Intelligence integration, are described and discussed.

引用

页数：23

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