Manufacture of Pharmaceutical Co-Crystals Using Twin Screw Extrusion: A Solvent-Less and Scalable Process

被引：99
|
作者：
Medina, Cesar [1 ]
Daurio, Dominick [1 ]
Nagapudi, Karthik [1 ]
Alvarez-Nunez, Fernando [1 ]
机构：
[1] Amgen Inc, Small Mol Proc & Prod Dev, Thousand Oaks, CA 91320 USA
来源：
JOURNAL OF PHARMACEUTICAL SCIENCES | 2010年 / 99卷 / 04期
关键词：
MOLECULAR-COMPLEXES; PHASE-DIAGRAMS; COCRYSTALS; ACID; SOLUBILITY; DRUG;
D O I：
10.1002/jps.21942
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
[No abstract available]
引用
收藏
页码：1693 / 1696
页数：4
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