Outcome of Very Low and Low Birth Weight Infants with Esophageal Atresia: Results of the Turkish Esophageal Atresia Registry

被引:19
|
作者
Oztan, Mustafa O. [1 ]
Soyer, Tutku [2 ]
Oztorun, Can, I [3 ]
Firinci, Binali [4 ]
Durakbasa, Cigdem U. [5 ]
Dokumcu, Zafer [6 ]
Gollu, Gulnur [7 ]
Akkoyun, Ibrahim [8 ]
Demirel, Dilek [9 ]
Karaman, Ayse [10 ]
Ciftci, Ilhan [11 ]
Ilhan, Huseyin [12 ]
Parlak, Ayse [13 ]
Ozden, Onder [14 ]
Comert, Hatice S. Y. [15 ]
Oral, Akgun [16 ]
Tekant, Gonca [17 ]
Kiyan, Gursu [18 ]
Erginel, Basak [19 ]
Guvenc, Unal [20 ]
Erdem, Ali Onur [21 ]
Erturk, Nazile [22 ]
Yildiz, Abdullah [23 ]
机构
[1] Izmir Katip Celebi Univ, Dept Pediat Surg, TR-35620 Izmir, Turkey
[2] Hacettepe Univ, Dept Pediat Surg, Ankara, Turkey
[3] Ankara Yildirim Beyazit Univ, Dept Pediat Surg, Ankara, Turkey
[4] Ataturk Univ, Dept Pediat Surg, Erzurum, Turkey
[5] Istanbul Medeniyet Univ, Dept Pediat Surg, Gortepe Training & Res Hosp, Istanbul, Turkey
[6] Ege Univ, Dept Pediat Surg, Izmir, Turkey
[7] Ankara Univ, Dept Pediat Surg, Ankara, Turkey
[8] Konya Educ & Res Hosp, Dept Pediat Surg, Konya, Turkey
[9] Ondokuz Mayis Univ, Dept Pediat Surg, Samsun, Turkey
[10] Univ Hlth Sci, Dr Sami Ulus Matern & Children Hlth & Res Applica, Dept Pediat Surg, Ankara, Turkey
[11] Selcuk Univ, Dept Pediat Surg, Konya, Turkey
[12] Eskisehir Osmangazi Univ, Dept Pediat Surg, Eskisehir, Turkey
[13] Uludag Univ, Dept Pediat Surg, Bursa, Turkey
[14] Cukurova Univ, Dept Pediat Surg, Adana, Turkey
[15] Karadeniz Tech Univ, Dept Pediat Surg, Trabzon, Turkey
[16] Dr Behcet Uz Educ & Res Hosp, Dept Pediat Surg, Izmir, Turkey
[17] Istanbul Univ Cerrahpasa, Dept Pediat Surg, Istanbul, Turkey
[18] Marmara Univ, Dept Pediat Surg, Istanbul, Turkey
[19] Istanbul Univ, Istanbul Fac Med, Dept Pediat Surg, Istanbul, Turkey
[20] Kanuni Sultan Suleyman Educ & Res Hosp, Dept Pediat Surg, Istanbul, Turkey
[21] Adnan Menderes Univ, Dept Pediat Surg, Aydin, Turkey
[22] Mugla Sitki Kocman Univ, Dept Pediat Surg, Ringgold Stand Inst, Mugla, Turkey
[23] Sisli Hamidiye Etfal Educ & Res Hosp, Dept Pediat Surg, Istanbul, Turkey
关键词
esophageal atresia; national registry; very low birth weight; low birth weight; SINGLE-CENTER EXPERIENCE; RISK-FACTORS; ATRESIA/TRACHEOESOPHAGEAL FISTULA; TRACHEOESOPHAGEAL FISTULA; PROGNOSTIC CLASSIFICATION; PRENATAL-DIAGNOSIS; PRIMARY REPAIR; PREVALENCE; SURVIVAL; CHILDREN;
D O I
10.1055/s-0040-1713663
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Introduction The data of the Turkish Esophageal Atresia Registry (TEAR) was evaluated to define the outcome of very low birth weight (VLBW) and low BW (LWB) infants with esophageal atresia (EA). Materials and Methods The data registered by 24 centers between 2014 and 2018 were evaluated for demographic features, prenatal findings, associated anomalies, surgical treatment, and outcome. Patients were enrolled in three groups according to their BWs (VLBW <1,500g), LWB=1,500-2,500g), and normal BW (NBW; >2,500g). Results Among the 389 cases, there were 37 patients (9.5%) in the VLBW group, 165 patients (42.4%) in the LBW group, and 187 patients (48.1%) in the NBW group. Prenatal diagnosis rates were similar among the three groups (29.7, 34.5, and 24.6%, respectively). The standard primary anastomosis was achieved at a significantly higher rate in NWB cases than in the other groups ( p <0.05). In patients with tracheoesophageal fistula (TEF), patients of the NBW group had significantly higher rates of full oral feedings, when compared with VLBW and LBW cases ( p <0.05). At the end of the first year, when we evaluate all patients, the number of cases with fistula recanalization and esophageal anastomotic strictures (AS) requiring esophageal dilatation was similar among the groups. The weight and height measurements at 6 months and 1 year of age of the survivors were similar in all the groups. The overall mortality rate was significantly higher in the VLBW and LBW groups, when compared with the NBW patients, even in patients with tension-free anastomosis ( p <0.05). The incidence of the associated anomalies was 90.6% in cases with mortality, which was significantly higher than in survivors (59.6%; p <0.05). According to Spitz's classification, the survival rate was 87.1% in class I, 55.3% in class II, and 16.7% in class III. The most common causes of mortality were associated with cardiovascular diseases, pneumonia, and sepsis. Conclusion The national data of TEAR demonstrates that the developmental and feeding parameters are better in NBW patients. Although VLBW patients have higher risk of developing fistula canalization than the LBW and NBW groups, long-term complications, such as anastomotic strictures, weight, and height values, after 1 year are similar in both groups. According to our results, associated anomalies and LBWs are still significant risk factors for mortality in cases with EA.
引用
下载
收藏
页码:226 / 235
页数:10
相关论文
共 50 条
  • [31] OUTCOME OF VERY VERY-LOW-BIRTH-WEIGHT INFANTS
    SELL, EJ
    CLINICS IN PERINATOLOGY, 1986, 13 (02) : 451 - 459
  • [32] OUTCOME OF VERY-LOW-BIRTH WEIGHT INFANTS
    LIEDEL, JW
    BOYD, BD
    BENDA, GI
    BABSON, SG
    PEDIATRIC RESEARCH, 1978, 12 (04) : 528 - 528
  • [33] OUTCOME FOR INFANTS OF VERY LOW-BIRTH-WEIGHT
    SILVERMAN, WA
    LANCET, 1981, 1 (8233): : 1319 - 1319
  • [34] MENTAL HEALTH IN INFANTS WITH ESOPHAGEAL ATRESIA
    Faugli, Anne
    Emblem, Ragnhild
    Bjornland, Kristin
    Diseth, Trond H.
    INFANT MENTAL HEALTH JOURNAL, 2009, 30 (01) : 40 - 56
  • [35] OUTCOME OF VERY-LOW-BIRTH-WEIGHT INFANTS
    ZMORA, E
    ISRAEL JOURNAL OF MEDICAL SCIENCES, 1995, 31 (05): : 327 - 329
  • [36] Lower esophageal banding in extremely low birth weight infants with esophageal atresia and tracheoesophageal fistula is a life saving practice followed by a successful delayed primary thoracoscopy reconstruction
    Margain, Loren
    Perez-Etchepare, Eduardo
    Varlet, Francois
    Lopez, Manuel
    JOURNAL OF PEDIATRIC SURGERY, 2015, 50 (03) : 489 - 492
  • [37] Respiratory status of infants with esophageal atresia
    D. A. Cozzi
    P. Capocaccia
    M. Roggini
    M. Matrunola
    F. Morini
    F. Cozzi
    Pediatric Surgery International, 2001, 17 : 92 - 96
  • [38] Respiratory status of infants with esophageal atresia
    Cozzi, DA
    Capocaccia, P
    Roggini, M
    Matrunola, M
    Morini, F
    Cozzi, F
    PEDIATRIC SURGERY INTERNATIONAL, 2001, 17 (2-3) : 92 - 96
  • [39] RESULTS OF CONVENTIONAL OPERATIVE PROCEDURES FOR ESOPHAGEAL ATRESIA IN PREMATURE INFANTS
    HAYS, DM
    SNYDER, WH
    AMERICAN JOURNAL OF SURGERY, 1963, 106 (01): : 19 - 23
  • [40] Are Low Weight or Cardiopathy Contraindications for Thoracoscopic Repair of Esophageal Atresia with Tracheoesophageal Fistula?
    Cadaval, Carlos
    Molino, Jose Andres
    Guillen, Gabriela
    Fernandez, Sergio Lopez
    Hierro, Carmen Lopez
    Rodriguez, Marta Martos
    Khan, Haider Ali
    Vilardell, Elena
    Andreu, Eva
    Ruiz, Cesar W.
    Lopez, Manuel
    EUROPEAN JOURNAL OF PEDIATRIC SURGERY, 2024, 34 (04) : 301 - 305