Role of Gut Microbiota and Probiotics in Colorectal Cancer: Onset and Progression

被引:42
|
作者
Torres-Maravilla, Edgar [1 ]
Boucard, Anne-Sophie [1 ]
Mohseni, Amir Hossein [2 ]
Taghinezhad-S, Sedigheh [2 ]
Cortes-Perez, Naima G. [3 ]
Bermudez-Humaran, Luis G. [1 ]
机构
[1] Univ Paris Saclay, Micalis Inst, AgroParisTech, INRAE, F-78350 Jouy En Josas, France
[2] Islamic Azad Univ, Fac Basic Sci, Dept Microbiol, Sci & Res Branch, Tehran 1477893855, Iran
[3] Univ Paris Saclay, AgroParisTech, INRAE, UMR 0496, F-78350 Jouy En Josas, France
关键词
microbiota; probiotics; lactic acid bacteria; cancer; colorectal cancer; POTENTIATES INTESTINAL TUMORIGENESIS; LACTIC-ACID BACTERIA; COLON-CANCER; LACTOBACILLUS-ACIDOPHILUS; ESCHERICHIA-COLI; CLINICAL-RELEVANCE; FECAL MICROBIOTA; LIVER-DISEASE; KAPPA-B; DYSBIOSIS;
D O I
10.3390/microorganisms9051021
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The gut microbiota plays an important role in maintaining homeostasis in the human body, and the disruption of these communities can lead to compromised host health and the onset of disease. Current research on probiotics is quite promising and, in particular, these microorganisms have demonstrated their potential for use as adjuvants for the treatment of colorectal cancer. This review addresses the possible applications of probiotics, postbiotics, synbiotics, and next-generation probiotics in colorectal cancer research.
引用
收藏
页数:24
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