Chronic hepatitis C associated with monoclonal gammopathy of undetermined significance

被引：7
|
作者：
Hamazaki, K
Baba, M
Hasegawa, H
Kai, M
Araki, M
Watanabe, N
Tuneya, Y
Kumazawa, M
Adachi, Y
机构：
[1] Mie Univ, Sch Med, Dept Internal Med 3, Tsu, Mie 514, Japan
[2] Mie Prefectural Gen Med Ctr, Dept Internal Med, Tsu, Mie, Japan
来源：
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | 2003年 / 18卷 / 04期
关键词：
case report; chronic hepatitis C; hepatitis C virus; lymphoproliferative disorders; monoclonal gammopathy of undetermined significance;
D O I：
10.1046/j.1440-1746.2003.02800.x
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Background: Two patients were admitted to Mie Prefectural General Medical Center and diagnosed as chronic hepatitis C complicated with monoclonal gammopathy of undetermined significance (MGUS). Methods: The MGUS class were immunoglobulin (Ig)G. The hepatitis C virus (HCV) RNA genotype was Ib. Based on these findings, they were diagnosed as chronic hepatitis C complicated with MGUS. Results: Histological studies showed chronic hepatitis in the liver and a mild rise in plasma cells without dysplasia and abnormalities in the bone marrow. Serum examination for cryoglobulin was negative. Conclusion: Chronic HCV infection might play a pathogenic role in the multistage process leading to lymphoproliferative disorders. (C) 2003 Blackwell Publishing Asia Pty Ltd.
引用
收藏
页码：459 / 460
页数：2
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