An efficient one-pot synthesis of C2-symmetric triazolophanes by copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction

被引：19
|
作者：
Rajesh, R. [1 ]
Periyasami, G. [1 ]
Raghunathan, R. [1 ]
机构：
[1] Univ Madras, Dept Organ Chem, Madras 600025, Tamil Nadu, India
来源：
TETRAHEDRON LETTERS | 2010年 / 51卷 / 14期
关键词：
1,3-Dipolar cycloaddition; Triazole; Click chemistry; Triazolophanes; CuAAC; 1,3-DIPOLAR CYCLOADDITIONS; CLICK; PEPTIDOTRIAZOLES; INHIBITORS; LIGATION;
D O I：
10.1016/j.tetlet.2010.02.020
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A facile and efficient one-pot synthesis of 12-15-membered triazolophanes has been accomplished using CuAAC methodology. The formation of triazolophanes was confirmed by spectral analysis and the products were isolated in good yield. The effect of solvents on this reaction was also studied. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1896 / 1898
页数：3
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