A Covalent Organic Framework with High Surface Area for Drug Delivery

被引:3
|
作者
Liu Xiaozhou [1 ,2 ]
Wang Yujie [2 ]
Liu Yaozu [2 ]
Li Zonglong [2 ]
Li Hui [2 ]
Fang Qianrong [2 ]
Jin Yongri [1 ]
机构
[1] Jilin Univ, Coll Chem, Changchun 130012, Jilin, Peoples R China
[2] Jilin Univ, State Key Lab Inorgan Synth & Preparat Chem, Changchun 130012, Jilin, Peoples R China
来源
基金
中国国家自然科学基金;
关键词
POLYMER; CRYSTALLINE; DESIGN;
D O I
10.7503/cjcu20190087
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We synthesized a novel 2D covalent organic framework ( COF) material with high surface area ( 1804 m2/g), denoted as JUC-516, which showed ideal result in the application of drug delivery in simulated body fluid ( SBF). Computational simulation by Materials Studio 7. 0 software, powder X-ray diffraction ( PXRD), N2 adsorption -desorption analysis, scanning electron microscope ( SEM) and Fourier transform infrared( FTIR) spectrascopy were carried out to prove the structure and property of JUC-516. JUC-516 was confirmed to be a covalent organic framework with hcb topology based on AA stack, high crystallinity and spherical morphology.
引用
收藏
页码:1813 / 1817
页数:5
相关论文
共 15 条
  • [1] Nanoscale covalent organic frameworks as smart carriers for drug delivery
    Bai, Linyi
    Phua, Soo Zeng Fiona
    Lim, Wei Qi
    Jana, Avijit
    Luo, Zhong
    Tham, Huijun Phoebe
    Zhao, Lingzhi
    Gao, Qiang
    Zhao, Yanli
    [J]. CHEMICAL COMMUNICATIONS, 2016, 52 (22) : 4128 - 4131
  • [2] Solution-processed, organophilic membrane derived from a polymer of intrinsic microporosity
    Budd, PM
    Elabas, ES
    Ghanem, BS
    Makhseed, S
    McKeown, NB
    Msayib, KJ
    Tattershall, CE
    Wang, D
    [J]. ADVANCED MATERIALS, 2004, 16 (05) : 456 - +
  • [3] Porous, crystalline, covalent organic frameworks
    Côté, AP
    Benin, AI
    Ockwig, NW
    O'Keeffe, M
    Matzger, AJ
    Yaghi, OM
    [J]. SCIENCE, 2005, 310 (5751) : 1166 - 1170
  • [4] Construction of Covalent Organic Framework for Catalysis: Pd/COF-LZU1 in Suzuki-Miyaura Coupling Reaction
    Ding, San-Yuan
    Gao, Jia
    Wang, Qiong
    Zhang, Yuan
    Song, Wei-Guo
    Su, Cheng-Yong
    Wang, Wei
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011, 133 (49) : 19816 - 19822
  • [5] Modular chemistry: Secondary building units as a basis for the design of highly porous and robust metal-organic carboxylate frameworks
    Eddaoudi, M
    Moler, DB
    Li, HL
    Chen, BL
    Reineke, TM
    O'Keeffe, M
    Yaghi, OM
    [J]. ACCOUNTS OF CHEMICAL RESEARCH, 2001, 34 (04) : 319 - 330
  • [6] 3D Porous Crystalline Polyimide Covalent Organic Frameworks for Drug Delivery
    Fang, Qianrong
    Wang, Junhua
    Gu, Shuang
    Kaspar, Robert B.
    Zhuang, Zhongbin
    Zheng, Jie
    Guo, Hongxia
    Qiu, Shilun
    Yan, Yushan
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2015, 137 (26) : 8352 - 8355
  • [7] Designed synthesis of large-pore crystalline polyimide covalent organic frameworks
    Fang, Qianrong
    Zhuang, Zhongbin
    Gu, Shuang
    Kaspar, Robert B.
    Zheng, Jie
    Wang, Junhua
    Qiu, Shilun
    Yan, Yushan
    [J]. NATURE COMMUNICATIONS, 2014, 5
  • [8] Storage of Hydrogen, Methane, and Carbon Dioxide in Highly Porous Covalent Organic Frameworks for Clean Energy Applications
    Furukawa, Hiroyasu
    Yaghi, Omar M.
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (25) : 8875 - 8883
  • [9] Conjugated microporous poly (aryleneethynylene) networks
    Jiang, Jia-Xing
    Su, Fabing
    Trewin, Abbie
    Wood, Colin D.
    Campbell, Nell L.
    Niu, Hongjun
    Dickinson, Calum
    Ganin, Alexey Y.
    Rosseinsky, Matthew J.
    Khimyak, Yaroslav Z.
    Cooper, Andrew I.
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (45) : 8574 - 8578
  • [10] Porous, covalent triazine-based frameworks prepared by ionothermal synthesis
    Kuhn, Pierre
    Antonietti, Markus
    Thomas, Arne
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2008, 47 (18) : 3450 - 3453