The Role of Inflammation in Patients with Chronic Heart Failure

Aims: To investigate the contributory role of Inflammation in the genesis of Heart Failure in the hospitalized patients of Arar, K.S.A and thereby strengthen the knowledge of Medical fraternity with regards to mechanism of Cardiac Failure Study design-Hospital Based Cross Sectional Study Place of study-The study was conducted in Prince Abdullah Bin musaed cardiac centre Arar, K.S.A Methods-The sample study included 50 cases in which inflammatory markers[CRP,CBP,ESR] where studied by collection of values of patients with chronic Heart failure from hospital records and analyzed by comparing their pre-treatment and post treatment levels by Spss16.0[Paired T Test] Results- Study showed the observation of significant P value[<0.05] for CRP,PLR,ESR With following values 1. CRP[P-<0.05],Mean[13.99 and 1.68],[S.D-11.15 and 6.0] 2. TLC-[P->0.05],Mean[12155 and 12100],S.D[11030 and 14163] 3. PLR[P<0.05],Mean[119 and 130] S.D[22.20 and 27.28] 4. ESR[P<0.05] Mean[11.04 and 5.32] S.D[17.06 and 5.15] Conclusion: In view of the significant P value[<0.05] for CRP, PLR,ESR, suggestions can be made for these markers to be used in Patients with Chronic Heart Failure.