Effect of Vitex rotundifolia on immediate-type allergic reaction

被引：27

作者：

Shin, TY

Kim, SH

Lim, JP

Suh, ES

Jeong, HJ

Kim, BD

Park, EJ

Hwang, WJ

Rye, DG

Baek, SH

An, NH

Kim, HM ^{[1
]}

机构：

[1] Wonkwang Univ, Coll Pharm, Iksan 570749, Chonbuk, South Korea

[2] Wonkwang Univ, Ctr Oriental Med Sci, Iksan 570749, Chonbuk, South Korea

[3] Woosuk Univ, Coll Pharm, Wanju 565701, Chonbuk, South Korea

[4] Wonkwang Univ, Coll Oriental Med, Iksan 570749, Chonbuk, South Korea

[5] Wonkwang Univ, Profess Grad Sch Oriental Med BK 21, Dept Nat Prod, Iksan 570749, Chonbuk, South Korea

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2000年 / 72卷 / 03期

关键词：

vitex rotundifolia fruits; immediate-type allergic reaction; compound; 48/80; rat peritoneal mast cells; passive cutaneous anaphylaxis; tumor necrosis factor-alpha;

D O I：

10.1016/S0378-8741(00)00258-0

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

We investigated the effect of aqueous extract of Vitex rotundifolia (L.) (Verbenaceae) fruits (VRFE) on the immediate-type allergic reactions in vivo and in vitro. VRFE (10(-4)-1.0 g/kg) dose-dependently inhibited systemic allergic reaction induced by compound 48/80. When VRFE was employed in a systemic allergic reaction test, the plasma histamine levels were reduced in a dose-dependent manner. VRFE (5 x 10(-1) and 1.0 g/kg) inhibited passive cutaneous anaphylaxis activated by anti-dinitrophenyl (DNP) IgE. VRFE (10(-3)-1.0 mg/ml) also dose-dependently inhibited the histamine release from the rat peritoneal mast cells (RPMC) by compound 48/80 or anti-DNP IgE. Moreover, VRFE (10(-3) mg/ml) had a significant inhibitory effect on anti-DNP IgE-induced tumor necrosis factor-alpha production from RPMC. These results suggest that VRFE may be beneficial in the regulation of immediate-type allergic reaction. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：443 / 450

页数：8

共 50 条

[31] CLASSIFICATION OF IMMEDIATE-TYPE, LIFE-THREATENING ALLERGIC OR PSEUDOALLERGIC REACTIONS
PATTERSON, R
DYKEWICZ, MS
GRAMMER, LC
GREENBERGER, PA
LAWRENCE, ID
WALKER, CL
WONG, S
ZEISS, CR
CHEST, 1990, 98 (02) : 257 - 259
[32] Inhibition of immediate-type allergic reactions by the aqueous extract of Salvia plebeia
Shin, TY
Kim, HM
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, 2002, 24 (02) : 303 - 314
[33] Control of allergic immune responses of the immediate-type by regulatory T cells
Bellinghausen, I.
Saloga, J.
ALLERGOLOGIE, 2008, 31 (06) : 208 - 212
[34] Immediate-type allergy to Omeprazole with systemic Reaction to Skin testing
Soubeiran, E.
Mueller, S.
Jakob, T.
JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2012, 10 : 3 - 3
[35] ANAPHYLACTIC REACTION TO LATEX, AN INCREASINGLY IMPORTANT IMMEDIATE-TYPE ALLERGEN
FABRO, L
MUHLETHALER, K
WUTHRICH, B
HAUTARZT, 1989, 40 (04): : 208 - 211
[36] ALLERGIC REACTION OF THE IMMEDIATE TYPE TO TETRACYCLIN
SAVCHAK, VI
VESTNIK DERMATOLOGII I VENEROLOGII, 1979, (07) : 54 - 55
[37] THE EFFECT OF IMMEDIATE-TYPE GASTROINTESTINAL ALLERGIC REACTIONS ON BRUSH-BORDER ENZYMES AND GUT MORPHOLOGY IN THE RAT
FREIER, S
ERAN, M
GOLDSTEIN, R
PEDIATRIC RESEARCH, 1985, 19 (05) : 456 - 459
[38] Inhibitory effect of mast cell-mediated immediate-type allergic reactions in rats by Perilla frutescens
Shin, TY
Kim, SH
Kim, SH
Kim, YK
Park, HJ
Chae, BS
Jung, HJ
Kim, HM
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, 2000, 22 (03) : 489 - 500
[39] EFFECT OF ABLATION OF EOSINOPHILS ON IMMEDIATE-TYPE HYPERSENSITIVITY REACTIONS
GLEICH, GJ
OLSON, GM
LOEGERING, DA
IMMUNOLOGY, 1979, 38 (02) : 343 - 353
[40] Aspirin: effect on development of immediate-type hypersensitivity to foods
Reactions Weekly, 2001, 874 (1) : 3 - 3

← 1 2 3 4 5 →