Recent Trends of the Bio-Inspired Nanoparticles in Cancer Theranostics

被引：105
|
作者：
Madamsetty, Vijay Sagar [1 ]
Mukherjee, Anubhab [2 ]
Mukherjee, Sudip [3 ]
机构：
[1] Mayo Clin, Coll Med & Sci, Dept Biochem & Mol Biol, Jacksonville, FL 32224 USA
[2] Sealink Pharmaceut, Dept Formulat, Hyderabad, India
[3] Rice Univ, Dept Bioengn, Houston, TX 77005 USA
来源：
FRONTIERS IN PHARMACOLOGY | 2019年 / 10卷
关键词：
bio-inspired nanoparticles; cancer; theranostics; nanomedicine; imaging; clinical trials; SOLID LIPID NANOPARTICLES; ALBUMIN-BASED NANOPARTICLES; DRUG-DELIVERY; SILVER NANOPARTICLES; VIRAL NANOPARTICLES; GOLD NANOPARTICLES; CONTRAST AGENTS; GREEN SYNTHESIS; QUANTUM DOTS; PHOTODYNAMIC THERAPY;
D O I：
10.3389/fphar.2019.01264
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
In recent years, various nanomaterials have emerged as an exciting tool in cancer theranostic applications due to their multifunctional property and intrinsic molecular property aiding effective diagnosis, imaging, and successful therapy. However, chemically synthesized nanoparticles have several issues related to the cost, toxicity and effectiveness. In this context, bio-inspired nanoparticles (NPs) held edges over conventionally synthesized nanoparticles due to their low cost, easy synthesis and low toxicity. In this present review article, a detailed overview of the cancer theranostics applications of various bio-inspired has been provided. This includes the recent examples of liposomes, lipid nanoparticles, protein nanoparticles, inorganic nanoparticles, and viral nanoparticles. Finally, challenges and the future scopes of these NPs in cancer therapy and diagnostics applications are highlighted.
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页数：12
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