Baricity variation in a spinal anaesthesia mixture for caesarean section. Does it have any effect on anaesthetic quality? A randomised, double blind, controlled study

Introduction: This study was conducted to compare the effectiveness subarachnoid anaesthesia with bupivacaine plus fentanyl at different concentrations of dextrose for caesarean section. Methods: A double-blind, randomised study, which included 60 patients, aged between 18 and 40 years, ASA I-II for caesarean section class 3 or 4, divided into 3 groups, designated A, B, and C corresponding to dextrose 2, 4 and 6%, respectively, bupivacaine 6.25 mg plus fentanyl 25 mu g. Demographic characteristics were quantified, episodes of hypotension and bradycardia onset and duration of sensory block and motor block, surgeon and maternal satisfaction, adverse events and the effect of anaesthesia on the foetus and neonate. A p < .05 was considered statistically significant. Results: There was no difference in the demographic data, the three-anaesthetic mixture with dextrose were sufficient to provide level and duration of anesthesia for surgery. Maternal hypotension events were lower in group C (p < 0.05), the same group had lower external malleolus deep sensitivity (p < 0.05), only 5 cases were consistent with neonatal asphyxia, however the Apgar scores values were greater than 7 points, with satisfactory development. Conclusions: The three anaesthetic mixtures for subarachnoid anaesthesia with bupivacainefentanyl are clinically effective; however, the greater the amount of dextrose used the better block quality. (C) 2020 Elsevier Espa & ntilde;a, S.L.U. All rights reserved.