A novel classification method for aid decision of traditional Chinese patent medicines for stroke treatment

被引:5
|
作者
Zhao, Yufeng [1 ,2 ]
Liu, Bo [3 ]
He, Liyun [1 ]
Bai, Wenjing [1 ]
Yu, Xueyun [1 ]
Cao, Xinyu [1 ,2 ]
Luo, Lin [1 ]
Rong, Peijing [4 ]
Zhao, Yuxue [4 ]
Li, Guozheng [2 ,5 ]
Liu, Baoyan [2 ,5 ]
机构
[1] China Acad Chinese Med Sci, Inst Basic Res Clin Med, Beijing 100700, Peoples R China
[2] China Acad Chinese Med Sci, Natl Data Ctr Tradit Chinese Med, Beijing 100700, Peoples R China
[3] Qingdao Hiser Hosp, Qingdao 266033, Peoples R China
[4] China Acad Chinese Med Sci, Inst Acupuncture & Moxibust, Beijing 100700, Peoples R China
[5] China Acad Chinese Med Sci, Beijing 100700, Peoples R China
基金
中国国家自然科学基金;
关键词
traditional Chinese patent medicines; stroke; aid decision; data mining; manifold ranking;
D O I
10.1007/s11684-017-0511-1
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Traditional Chinese patent medicines are widely used to treat stroke because it has good efficacy in the clinical environment. However, because of the lack of knowledge on traditional Chinese patent medicines, many Western physicians, who are accountable for the majority of clinical prescriptions for such medicine, are confused with the use of traditional Chinese patent medicines. Therefore, the aid-decision method is critical and necessary to help Western physicians rationally use traditional Chinese patent medicines. In this paper, Manifold Ranking is employed to develop the aid-decision model of traditional Chinese patent medicines for stroke treatment. First, 115 stroke patients from three hospitals are recruited in the cross-sectional survey. Simultaneously, traditional Chinese physicians determine the traditional Chinese patent medicines appropriate for each patient. Second, particular indicators are explored to characterize the population feature of traditional Chinese patent medicines for stroke treatment. Moreover, these particular indicators can be easily obtained byWestern physicians and are feasible for widespread clinical application in the future. Third, the aid-decision model of traditional Chinese patent medicines for stroke treatment is constructed based on Manifold Ranking. Experimental results reveal that traditional Chinese patent medicines can be differentiated. Moreover, the proposed model can obtain high accuracy of aid decision.
引用
收藏
页码:432 / 439
页数:8
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