Exploiting Transient Radical Cations as Bronsted Acids for Allylic C-H Heteroarylation of Enol Silyl Ethers

被引：15
|
作者：
Nakashima, Tsubasa [1 ,2 ]
Fujimori, Haruka [1 ,2 ]
Ohmatsu, Kohsuke [1 ,2 ]
Ooi, Takashi [1 ,2 ]
机构：
[1] Nagoya Univ, Grad Sch Engn, Inst Transformat Biomol WPI ITbM, Nagoya, Aichi 4648601, Japan
[2] Nagoya Univ, Grad Sch Engn, Dept Mol & Macromol Chem, Nagoya, Aichi 4648601, Japan
来源：
CHEMISTRY-A EUROPEAN JOURNAL | 2021年 / 27卷 / 36期
关键词：
C-H functionalization; enol silyl ethers; heteroarylation; photoredox catalysis; radical cations; SUBSTITUTION-REACTION; ELECTRON-TRANSFER; ARYLATION; CYCLOADDITIONS; REACTIVITY;
D O I：
10.1002/chem.202101352
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Intermediary radical cations, generated through single-electron oxidation of enol silyl ethers by excited Ir-based photocatalysts, can be exploited as Bronsted acids for the activation of heteroarylcyanides. This strategy enables the direct allylic C-H heteroarylation of enol silyl ethers under visible-light irradiation.
引用
收藏
页码：9253 / 9256
页数：4
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