Synthesis of substituted 2-mercaptobenzaldehydes and 2-substituted benzo[b]thiophenes

被引：32
|
作者：
Gallagher, T
Pardoe, DA
Porter, RA
机构：
[1] Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon, England
[2] SB Pharmaceut, Discovery Res, Harlow CM19 5AW, Essex, England
来源：
TETRAHEDRON LETTERS | 2000年 / 41卷 / 28期
关键词：
D O I：
10.1016/S0040-4039(00)00870-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Simple and rapid single-pot preparations of substituted 2-mercaptobenzaldehydes 5 and 2-substituted benzo[b]thiophenes 3 based on ortho-lithiation methodology are described. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：5415 / 5418
页数：4
相关论文
共 50 条
  • [1] SYNTHESIS AND PHARMACOLOGICAL PROPERTIES OF SOME NEW 2-SUBSTITUTED BENZO [b] THIOPHENES
    Naganagowda, Gadada
    Petsom, Amorn
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2011, 21 (01) : 85 - 92
  • [2] Titanium reagents for the synthesis of 2-substituted benzo[b]thiophenes on the solid phase
    Roberts, CF
    Hartley, RC
    JOURNAL OF ORGANIC CHEMISTRY, 2004, 69 (18): : 6145 - 6148
  • [3] Trithiocarbonate Anion as a Sulfur Source for the Synthesis of 2,5-Disubstituted Thiophenes and 2-Substituted Benzo[b]thiophenes
    Paixao, Douglas B.
    Rampon, Daniel S.
    Salles, Helena D.
    Soares, Eduardo G. O.
    Bilheri, Filipe N.
    Schneider, Paulo H.
    JOURNAL OF ORGANIC CHEMISTRY, 2020, 85 (20): : 12922 - 12934
  • [4] SYNTHESIS OF SUBSTITUTED BENZO[B]THIOPHENES
    RIED, W
    OREMEK, G
    OCAKCIOGLU, B
    LIEBIGS ANNALEN DER CHEMIE, 1980, (09): : 1424 - 1427
  • [5] Investigation on the One-Step Preparation of 2-Substituted Benzo[B]Thiophenes
    Zhao, Qian
    Qian, Chao
    Chen, Xin-Zhi
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2013, 188 (07) : 873 - 878
  • [6] 2-SUBSTITUTED BENZO[B]TELLUROPHENES
    PIETTE, JL
    TALBOT, JM
    GENARD, JC
    RENSON, M
    BULLETIN DE LA SOCIETE CHIMIQUE DE FRANCE PARTIE II-CHIMIE MOLECULAIRE ORGANIQUE ET BIOLOGIQUE, 1973, (7-8): : 2468 - 2471
  • [7] Synthesis and pharmacological evaluation of 2-substituted benzo[b]thiophenes as anti-inflammatory and analgesic agents
    Fakhr, Issa M. I.
    Radwan, Mohamed A. A.
    El-Batran, Seham
    El-Salam, Omar M. E. Abd
    El-Shenawy, Siham M.
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2009, 44 (04) : 1718 - 1725
  • [8] Straightforward Synthesis of 2-Acetyl-Substituted Benzo[b]thiophenes
    Debray, Julien
    Lemaire, Marc
    Popowycz, Florence
    SYNLETT, 2013, 24 (01) : 37 - 40
  • [9] TAUTOMERISM OF 2-SUBSTITUTED BENZO[B]THIOPHENES . ULTRAVIOLET SPECTRAL CORRELATION OF TAUTOMER STRUCTURE WITH AROMATICITY
    STACY, GW
    WOLLNER, TE
    JOURNAL OF ORGANIC CHEMISTRY, 1967, 32 (10): : 3028 - &
  • [10] MPHT-Promoted Bromocyclization of ortho-Substituted Arylalkynes: Application to the Synthesis of 2-Substituted 3-Bromobenzofurans and -Benzo[b]thiophenes
    Jacubert, Maud
    Tikad, Abdellatif
    Provot, Olivier
    Hamze, Abdallah
    Brion, Jean-Daniel
    Alami, Mouad
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2010, 2010 (23) : 4492 - 4500
12345