Transwell stroma culture in the presence of FLT-ligand and thrombopoietin allows ex vivo expansion and gene transfer in NOD/SCID mice repopulating CD34+CD38- cells.

被引:0
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作者
Bertolini, F
Battaglia, M
Lanza, A
Palermo, B
Soligo, D
dellaCuna, GR
机构
[1] IRCCS,MAUGERI FDN,PAVIA,ITALY
[2] IRCCS,MAGGIORE HOSP,BMT UNIT,PAVIA,ITALY
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R5 [内科学];
学科分类号
1002 ; 100201 ;
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页码:1626 / 1626
页数:1
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  • [1] Engraftment in NOD/SCID mice of human CD34+ cord blood cells after ex vivo expansion:: Evidence for the amplification and self-renewal of repopulating stem cells.
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