QTc prolongation and Torsades de Pointes associated with methadone therapy

被引：21

作者：

Routhier, Denise D.

Katz, Kenneth D.

Brooks, Daniel E.

机构：

[1] Univ Pittsburgh, Presbyterian Hosp, Med Ctr, Dept Emergency Med, Pittsburgh, PA 15213 USA

[2] Univ Pittsburgh, Presbyterian Hosp, Med Ctr, Div Med Toxicol, Pittsburgh, PA 15213 USA

来源：

JOURNAL OF EMERGENCY MEDICINE | 2007年 / 32卷 / 03期

关键词：

methadone; QTc prolongation; Torsades de Pointes; HIV; dysrhythmia;

D O I：

10.1016/j.jemermed.2006.07.027

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Oral methadone therapy is an effective and increasingly popular treatment for opioid dependency and chronic pain. Although it is not typically considered pro-dysrhythmic, we present the unique case of a 52-year-old HIV-positive woman without underlying cardiac disease who developed QTc prolongation and pulseless Torsades secondary to high dose methadone therapy. (C) 2007 Elsevier Inc.

引用

页码：275 / 278

页数：4

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