QTc prolongation and Torsades de Pointes associated with methadone therapy

被引:21
|
作者
Routhier, Denise D.
Katz, Kenneth D.
Brooks, Daniel E.
机构
[1] Univ Pittsburgh, Presbyterian Hosp, Med Ctr, Dept Emergency Med, Pittsburgh, PA 15213 USA
[2] Univ Pittsburgh, Presbyterian Hosp, Med Ctr, Div Med Toxicol, Pittsburgh, PA 15213 USA
来源
JOURNAL OF EMERGENCY MEDICINE | 2007年 / 32卷 / 03期
关键词
methadone; QTc prolongation; Torsades de Pointes; HIV; dysrhythmia;
D O I
10.1016/j.jemermed.2006.07.027
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Oral methadone therapy is an effective and increasingly popular treatment for opioid dependency and chronic pain. Although it is not typically considered pro-dysrhythmic, we present the unique case of a 52-year-old HIV-positive woman without underlying cardiac disease who developed QTc prolongation and pulseless Torsades secondary to high dose methadone therapy. (C) 2007 Elsevier Inc.
引用
收藏
页码:275 / 278
页数:4
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