Mechanisms of Resistance to Cancer Chemotherapy

被引:0
|
作者
Stefanko, Ewa [1 ]
Wrobel, Tomasz [1 ]
机构
[1] Wroclaw Med Univ, Dept Hematol Blood Neoplasms & Bone Marrow Transp, PL-50367 Wroclaw, Poland
来源
关键词
resistance to chemotherapy; cancer cells; leukemia; lymphomas; ACUTE LYMPHOBLASTIC-LEUKEMIA; ACUTE MYELOID-LEUKEMIA; DNA MISMATCH REPAIR; PROGNOSTIC-SIGNIFICANCE; CELL LYMPHOMAS; EXPRESSION; CISPLATIN; GENE; MDR1; SURVIVIN;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Resistance to chemotherapy is one of the major causes of failure of anticancer treatment. It can occur at every level of the drug action and includes mechanisms such as increased drug efflux and decreased influx, drug inactivation, alterations in the drug target, DNA damage repair, and evasion of apoptosis. In this article some mechanisms of drug resistance in cancer chemotherapy are reviewed (Adv Clin Exp Med 2010, 19, 1, 5-12).
引用
下载
收藏
页码:5 / 12
页数:8
相关论文
共 50 条
  • [1] Resistance mechanisms to cancer chemotherapy
    Redmond, Kelly Marie
    Wilson, Timothy Richard
    Johnston, Patrick Gerard
    Longley, Daniel Broderick
    FRONTIERS IN BIOSCIENCE-LANDMARK, 2008, 13 : 5138 - 5154
  • [2] Mechanisms of Multidrug Resistance in Cancer Chemotherapy
    Bukowski, Karol
    Kciuk, Mateusz
    Kontek, Renata
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (09)
  • [3] Novel mechanisms of resistance to cancer chemotherapy
    Singh, G
    Dorward, A
    Moorehead, R
    Sweet, S
    CANCER JOURNAL - FRANCE, 1995, 8 (06): : 304 - 307
  • [4] Mechanisms of Drug Resistance in Cancer Chemotherapy
    Luqmani, Y. A.
    MEDICAL PRINCIPLES AND PRACTICE, 2005, 14 : 35 - 48
  • [5] Mechanisms of Resistance to Chemotherapy in Gastric Cancer
    Marin, J. J. G.
    Al-Abdulla, R.
    Lozano, E.
    Briz, O.
    Bujanda, L.
    Banales, J. M.
    Macias, R. I. R.
    ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2016, 16 (03) : 318 - 334
  • [6] Mechanisms of chemotherapy resistance in ovarian cancer
    Ortiz, Mylena
    Wabel, Emma
    Mitchell, Kerry
    Horibata, Sachi
    CANCER DRUG RESISTANCE, 2022, 5 (02) : 304 - 316
  • [7] Mechanisms and consequences of chemotherapy resistance in breast cancer
    Coley, Helen M.
    EJC SUPPLEMENTS, 2009, 7 (01): : 3 - 7
  • [8] Cellular resistance mechanisms in cancer and the new approaches to overcome resistance mechanisms chemotherapy
    Al Saihati, Hajir A.
    Rabaan, Ali A.
    SAUDI MEDICAL JOURNAL, 2023, 44 (04) : 329 - 344
  • [10] Insights into molecular mechanisms of chemotherapy resistance in cancer
    Kar, Animesh
    Agarwal, Shivam
    Singh, Agrata
    Bajaj, Avinash
    Dasgupta, Ujjaini
    TRANSLATIONAL ONCOLOGY, 2024, 42