Preparation, characterization, and catalytic application of metallic nanocrystalline MgAl2O4 in the synthesis of 3-hydroxy-3-indolyl-indolin-2-ones, symmetrical and unsymmetrical 3,3′-bis(indolyl)indolin-2-ones, and 3,3′-bis(indolyl)methanes

被引：8

作者：

Nikoofar, Kobra ^{[1
]}

Haghighi, Maryam ^{[1
]}

Khademi, Zahra ^{[1
]}

机构：

[1] Alzahra Univ, Fac Phys & Chem, Dept Chem, POB 1993893973, Tehran, Iran

来源：

ARABIAN JOURNAL OF CHEMISTRY | 2019年 / 12卷 / 08期

关键词：

MgAl2O4; Oxindoles; Nanocatalyst; Multi-component reaction (MCR); FRIEDEL-CRAFTS ALKYLATION; REUSABLE CATALYST; FACILE SYNTHESIS; EFFICIENT; SPINEL; DERIVATIVES; 3,3-DI(INDOLYL)INDOLIN-2-ONES; OXINDOLES; SUPPORT; INDOLES;

D O I：

10.1016/j.arabjc.2016.01.013

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Nanocrystalline MgAl2O4 has been synthesized via co-precipitation method and characterized by Fourier transform infrared spectroscopy (FT-IR), energy-dispersive X-ray spectroscopy (EDX), scanning electron microscopy (SEM), and X-ray diffraction (XRD) techniques. The synthesized nanocatalyst has been utilized for the one-pot condensation of indoles and isatins to prepare 3-hydroxy-3-indolyl-indolin-2-ones and symmetrical and unsymmetrical 3,3'-bis(indolyl)-indolin-2-ones. The one-pot pseudo three-component condensation of indoles and various aldehydes has also been examined to afford 3,3'-bis(indolyl)methanes. Short reaction times, reusability and recovery of the nanocatalyst, in addition to solvent-free reaction media are some advantages of this eco-friendly procedure. (C) 2019 Published by Elsevier B.V. on behalf of King Saud University.

引用

页码：3776 / 3784

页数：9

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