Preparation, characterization, and catalytic application of metallic nanocrystalline MgAl2O4 in the synthesis of 3-hydroxy-3-indolyl-indolin-2-ones, symmetrical and unsymmetrical 3,3′-bis(indolyl)indolin-2-ones, and 3,3′-bis(indolyl)methanes

被引：8
|
作者：
Nikoofar, Kobra [1 ]
Haghighi, Maryam [1 ]
Khademi, Zahra [1 ]
机构：
[1] Alzahra Univ, Fac Phys & Chem, Dept Chem, POB 1993893973, Tehran, Iran
来源：
ARABIAN JOURNAL OF CHEMISTRY | 2019年 / 12卷 / 08期
关键词：
MgAl2O4; Oxindoles; Nanocatalyst; Multi-component reaction (MCR); FRIEDEL-CRAFTS ALKYLATION; REUSABLE CATALYST; FACILE SYNTHESIS; EFFICIENT; SPINEL; DERIVATIVES; 3,3-DI(INDOLYL)INDOLIN-2-ONES; OXINDOLES; SUPPORT; INDOLES;
D O I：
10.1016/j.arabjc.2016.01.013
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Nanocrystalline MgAl2O4 has been synthesized via co-precipitation method and characterized by Fourier transform infrared spectroscopy (FT-IR), energy-dispersive X-ray spectroscopy (EDX), scanning electron microscopy (SEM), and X-ray diffraction (XRD) techniques. The synthesized nanocatalyst has been utilized for the one-pot condensation of indoles and isatins to prepare 3-hydroxy-3-indolyl-indolin-2-ones and symmetrical and unsymmetrical 3,3'-bis(indolyl)-indolin-2-ones. The one-pot pseudo three-component condensation of indoles and various aldehydes has also been examined to afford 3,3'-bis(indolyl)methanes. Short reaction times, reusability and recovery of the nanocatalyst, in addition to solvent-free reaction media are some advantages of this eco-friendly procedure. (C) 2019 Published by Elsevier B.V. on behalf of King Saud University.
引用
收藏
页码：3776 / 3784
页数：9
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