Management of gout: beyond allopurinol

被引：5
|
作者：
McGill, N. W. [1 ]
机构：
[1] Royal Prince Alfred Hosp, Dept Rheumatol, Sydney, NSW 2071, Australia
来源：
INTERNAL MEDICINE JOURNAL | 2010年 / 40卷 / 08期
关键词：
rheumatology; gout; allopurinol; febuxostat; SERUM URIC-ACID; TOPHACEOUS GOUT; SYNOVIAL-FLUID; RENAL-FUNCTION; INCIDENT GOUT; ADVERSE EVENTS; RISK; URATE; MEN; HYPERURICEMIA;
D O I：
10.1111/j.1445-5994.2010.02293.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The basic concepts of the pathogenesis and management of gout have not altered for many years. Monosodium urate monohydrate crystals drive the disease and identification of these crystals is required for certain diagnosis. In contrast, our understanding of the mediators of gouty inflammation, the appropriate target serum urate concentration during treatment, the drugs available and the best ways to use those drugs have all advanced in recent years and will be the focus of this review.
引用
收藏
页码：545 / 553
页数：9
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