Covalent immobilization of oligonucleotides on modified glass/silicon surfaces for solid-phase DNA hybridization and amplification

被引：28
|
作者：
Yang, MS [1 ]
Kong, RYC [1 ]
Kazmi, N [1 ]
Leung, AKC [1 ]
机构：
[1] City Univ Hong Kong, Dept Biol & Chem, Kowloon, Hong Kong
来源：
CHEMISTRY LETTERS | 1998年 / 03期
关键词：
D O I：
10.1246/cl.1998.257
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Glass slides and silicon chips were modified with aminosilane and various linker molecules to provide activated surfaces for covalent immobilization of oligonucleotides under ambient condition, and the surface-attached oligonucleotides remain active for solid-phase DNA hybridization and polymerase chain reaction.
引用
收藏
页码：257 / 258
页数：2
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