Cycloartane triterpenoid saponins from the herbs of Thalictrum fortunei

被引：5

作者：

Jiang, Si-Qi ^{[1
,2
]}

Zhang, Yu-Bo ^{[1
,2
]}

Xiao, Min ^{[3
,4
]}

Jiang, Lin ^{[1
,2
]}

Luo, Ding ^{[1
,2
]}

Niu, Qian-Wen ^{[1
,2
]}

Li, Yao-Lan ^{[1
,2
]}

Zhang, Xian-Tao ^{[3
,4
]}

Wang, Guo-Cai ^{[1
,2
]}

机构：

[1] Jinan Univ, Coll Pharm, Inst Tradit Chinese Med & Nat Prod, Guangzhou 510632, Guangdong, Peoples R China

[2] Jinan Univ, Guangdong Prov Key Lab Pharmacodynam Constituents, Guangzhou 510632, Guangdong, Peoples R China

[3] Guangdong Inst Tradit Chinese Med, Guangzhou 510520, Guangdong, Peoples R China

[4] Guangzhou Univ Chinese Med, Guangzhou 510006, Guangdong, Peoples R China

来源：

CARBOHYDRATE RESEARCH | 2017年 / 445卷

基金：

中国国家自然科学基金;

关键词：

Thalictrum fortunei; Cycloartane triterpenoid saponins; Cytotoxicity; Antiviral activity; BENZYLISOQUINOLINE ALKALOIDS; GLYCOSIDES; CONSTITUENTS; PLANTS; MINUS;

D O I：

10.1016/j.carres.2017.03.019

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Six new cycloartane triterpenoid saponins, thalisides A-F (1-6), along with four known ones (7-10), were isolated from Thalictrum fortunei. The new structures were elucidated by using spectroscopic data (NMR, IR, UV, and MS). Compounds 1-10 were examined for their in vitro cytotoxicity against two human cancer cell lines (HepG2, A549) and antiviral activity against influenza A virus (H1N1) and found to be inactive. (C) 2017 Elsevier Ltd. All rights reserved.

引用

页码：1 / 6

页数：6

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