Endometrial stem cells: clinical application and pathological roles

被引:0
|
作者
Xu, Yanping [1 ]
Zhu, Huiting [1 ]
Zhao, Dongni [1 ]
Tan, Jichun [1 ]
机构
[1] China Med Univ, Dept Obstet & Gynecol, Reprod Med Ctr, Shengjing Hosp, 36,Sanhao St,Heping Sreet, Shenyang 110004, Liaoning, Peoples R China
关键词
Endometrial stem cells; menstrual blood-derived stem cells; molecular mechanisms; endometriosis; endometrial carcinoma; cancer stem cells; ENDOTHELIAL PROGENITOR CELLS; MENSTRUAL BLOOD; STEM/PROGENITOR CELLS; REGENERATIVE CELLS; MESENCHYMAL CELLS; OSTEOGENIC DIFFERENTIATION; SELF-RENEWAL; MOUSE MODEL; TRANSPLANTATION; EXPRESSION;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Adult stem cells occur in human endometrium. Menstrual-blood derived stem cells (MenSCs) are mesenchymal stem cells that can be obtained in a non-invasive manner. Due to their rapid proliferation rate, low immunogenicity, and low tumorigenicity, MenSCs are used extensively in tissue engineering. They can be induced into multiple cell lineages under certain conditions. MenSCs contribute to tissue repair via several different mechanisms, highlighting their great promise in clinical applications. Endometrial stem cells may also be used to shed light on the pathogenesis of endometriosis and endometrial carcinoma. This review will cover recent progress in this field.
引用
收藏
页码:22039 / 22044
页数:6
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