Is there a role of magnetic resonance imaging in deciding to stop anti-tumor necrosis factor treatment in ileal Crohn's disease?

被引：5

作者：

Gallego, Jose C. ^{[1
]}

Echarri, Ana ^{[2
]}

机构：

[1] Complexo Hosp Univ Ferrol, Radiol Dept, Av Residencia S-N, Ferrol 15405, Spain

[2] Complexo Hosp Univ Ferrol, Gastroenterol Dept, Ferrol, Spain

来源：

CLINICAL IMAGING | 2017年 / 43卷

关键词：

Crohn's disease; Magnetic resonance imaging; Anti-tumor necrosis factor agents; INFLAMMATORY-BOWEL-DISEASE; INFLIXIMAB THERAPY; CLINICAL REMISSION; FOLLOW-UP; DISCONTINUATION; MAINTENANCE; RELAPSE;

D O I：

10.1016/j.clinimag.2017.03.010

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Purpose: This study was performed to assess the ability of magnetic resonance enterography to predict the evolution of patients in whom anti-tumor necrosis factor-alpha therapy was suspended. Methods: A prospective study of patients with ileal Crohn's disease was performed. Results: Twenty-nine patients were included. Patients who later relapsed showed higher magnetic resonance scores than those who did not relapse (4.2 vs. 2.5, respectively; p < 0.02). The area under the receiving-operating characteristics curve was 0.755 when discriminating patients who relapsed. Conclusions: Magnetic resonance enterography should be taken into account when deciding the withdrawal of anti-tumor necrosis factor-alpha in patients with Crohn's disease. (C) 2017 Elsevier Inc. All rights reserved.

引用

页码：175 / 179

页数：5

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