RNase MRP RNA and human genetic diseases

被引：58
|
作者：
Martin, Allison N.
Li, Yong
机构：
[1] Univ Louisville, Dept Biochem & Mol Biol, Louisville, KY 40202 USA
[2] Univ Louisville, Sch Med, Ctr Genet & Mol Med, Louisville, KY 40202 USA
来源：
CELL RESEARCH | 2007年 / 17卷 / 03期
关键词：
RNase MRP RNA; cartilage-hair hypoplasia;
D O I：
10.1038/sj.cr.7310120
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
RNase MRP RNA is the RNA subunit of the RNase mitochondrial RNA processing (MRP) enzyme complex that is involved in multiple cellular RNA processing events. Mutations on RNase MRP RNA gene (RMRP) cause a recessively inherited developmental disorder, cartilage-hair hypoplasia (CHH). The relationship of the genotype (RMRP mutation), RNA processing deficiency of the RNase MRP complex, and the phenotype of CHH and other skeletal dysplasias is yet to be explored.
引用
收藏
页码：219 / 226
页数：8
相关论文
共 50 条
  • [21] RNase MRP and the RNA processing cascade in the eukaryotic ancestor
    Woodhams, Michael D.
    Stadler, Peter F.
    Penny, David
    Collins, Lesley J.
    BMC EVOLUTIONARY BIOLOGY, 2007, 7 (Suppl 1)
  • [22] RNase MRP and the RNA processing cascade in the eukaryotic ancestor
    Michael D Woodhams
    Peter F Stadler
    David Penny
    Lesley J Collins
    BMC Evolutionary Biology, 7
  • [23] THE RNA OF RNASE MRP IS REQUIRED FOR NORMAL PROCESSING OF RIBOSOMAL-RNA
    CHU, S
    ARCHER, RH
    ZENGEL, JM
    LINDAHL, L
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (02) : 659 - 663
  • [24] Sequence analysis of RNase MRP RNA reveals its origination from eukaryotic RNase P RNA
    Zhu, YL
    Stribinskis, V
    Ramos, KS
    Li, Y
    RNA, 2006, 12 (05) : 699 - 706
  • [25] Further characterization of human RNase MRP/RNase P and related autoantibodies
    Robert M. Karwan
    Molecular Biology Reports, 1998, 25 : 95 - 101
  • [26] Further characterization of human RNase MRP RNase P and related autoantibodies
    Karwan, RM
    MOLECULAR BIOLOGY REPORTS, 1998, 25 (02) : 95 - 101
  • [27] Functional equivalence of hairpins in the RNA subunits of RNase MRP and RNase P in Saccharomyces cerevisiae
    Lindahl, L
    Fretz, S
    Epps, N
    Zengel, JM
    RNA, 2000, 6 (05) : 653 - 658
  • [28] Heterodimerization of the human RNase P/MRP subunits Rpp20 and Rpp25 is a prerequisite for interaction with the P3 arm of RNase MRP RNA
    Hands-Taylor, Katherine L. D.
    Martino, Luigi
    Tata, Renee
    Babon, Jeffrey J.
    Bui, Tam T.
    Drake, Alex F.
    Beavil, Rebecca L.
    Pruijn, Ger J. M.
    Brown, Paul R.
    Conte, Maria R.
    NUCLEIC ACIDS RESEARCH, 2010, 38 (12) : 4052 - 4066
  • [29] SECONDARY STRUCTURE OF RNASE MRP RNA AS PREDICTED BY PHYLOGENETIC COMPARISON
    SCHMITT, ME
    BENNETT, JL
    DAIRAGHI, DJ
    CLAYTON, DA
    FASEB JOURNAL, 1993, 7 (01): : 208 - 213
  • [30] Viperin mRNA is a novel target for the human RNase MRP/RNase P endoribonuclease
    Mattijssen, Sandy
    Hinson, Ella R.
    Onnekink, Carla
    Hermanns, Pia
    Zabel, Bernhard
    Cresswell, Peter
    Pruijn, Ger J. M.
    CELLULAR AND MOLECULAR LIFE SCIENCES, 2011, 68 (14) : 2469 - 2480
12345