Tumor size matters differently in pulmonary adenocarcinoma and squamous cell carcinoma

被引：7
|
作者：
Lin, Pei-Ying
Chang, Yeun-Chung [2 ]
Chen, Hsuan-Yu [3 ]
Chen, Chen-Hao
Tsui, Hung-Chang
Yang, Pan-Chyr [1 ]
机构：
[1] Natl Taiwan Univ, Coll Med, Dept Internal Med, Natl Taiwan Univ Hosp, Taipei 100, Taiwan
[2] Natl Taiwan Univ Hosp, Dept Radiol, Taipei, Taiwan
[3] Acad Sinica, Inst Stat Sci, Taipei 11529, Taiwan
来源：
LUNG CANCER | 2010年 / 67卷 / 03期
关键词：
Non-small cell lung cancer (NSCLC); Adenocarcinoma; Squamous cell carcinoma; Size; Nodal/distant metastases; RECEPTOR GENE-MUTATIONS; LUNG-CANCER; NEVER-SMOKERS; RISK-FACTORS; STAGE-I; DISEASE; EPIDEMIOLOGY; IMPACT; CLASSIFICATION; METASTASIS;
D O I：
10.1016/j.lungcan.2009.04.017
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Little about primary tumor size and nodal/distant metastases among different cell types in non-small cell lung cancer (NSCLC) was discussed This study aimed to investigate distinct associations between tumor size and nodal/distant metastases in pulmonary adenocarcinoma and squamous cell carcinoma The study also aimed to clarify the cutoff size relating to a higher likelihood of metastases We retrospectively evaluated 932 NSCLC patients over a 3-year period and focused on cases with primary tumors less than 4.0 cm in size Our data showed that 2.5 cm was the critical cutoff size regarding increased nodal/distant metastases in adenocarcinoma (p <0.001), but not in squamous cell carcinoma (p > 0 05). In addition, the incidence of nodal/distant metastases reached a plateau of more than 80% in adenocarcinoma when the tumor size exceeded 2 5 cm In contrast, there was no such correlation observed in squamous cell carcinoma. This study showed that tumor size mattered differently in pulmonary adenocarcinoma and squamous cell carcinoma (C) 2009 Elsevier Ireland Ltd. All rights reserved
引用
收藏
页码：296 / 300
页数：5
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