We need stronger evidence for (or against) hepatocellular carcinoma surveillance

被引：29
|
作者：
Jepsen, Peter [1 ,2 ,3 ]
West, Joe [3 ,4 ,5 ]
机构：
[1] Aarhus Univ Hosp, Dept Gastroenterol & Hepatol, Palle Juul Jensens Blvd 99, DK-8200 Aarhus N, Denmark
[2] Aarhus Univ Hosp, Dept Clin Epidemiol, Aarhus, Denmark
[3] Univ Nottingham, Sch Med, Div Epidemiol & Publ Hlth, Nottingham, England
[4] Nottingham Univ Hosp NHS Trust, NIHR Nottingham Biomed Res Ctr BRC, Nottingham, England
[5] Univ Nottingham, Nottingham, England
来源：
JOURNAL OF HEPATOLOGY | 2021年 / 74卷 / 05期
关键词：
Screening; Prevention; Cancer; Epidemiology; COMPETING RISKS; CIRRHOSIS; LIVER; EPIDEMIOLOGY;
D O I：
10.1016/j.jhep.2020.12.029
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Current guidelines from EASL recommend that most patients with cirrhosis are offered surveillance for hepatocellular carcinoma (HCC), but fewer patients than expected actually receive it. The recommendation is based on observational studies and simulations, not randomised trials. In this opinion piece we argue that a randomised trial of HCC surveillance vs. no surveillance is necessary and feasible, and we believe that clinician and patient participation in HCC surveillance would be better if it were based on trial results demonstrating its value. (c) 2021 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码：1234 / 1239
页数：6
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