Wilms' tumour 1 mutations are associated with FLT3-ITD and failure of standard induction chemotherapy in patients with normal karyotype AML

被引：76
|
作者：
Summers, K. [1 ]
Stevens, J.
Kakkas, I.
Smith, M.
Smith, L. L.
MacDougall, F.
Cavenagh, J.
Bonnet, D.
Young, B. D.
机构：
[1] Barts & London Queen Marys Sch Med & Dent, Ctr Med Oncol, London, England
[2] Guys Hosp, Dept Hematol, London, England
[3] St Bartholomews Hosp, Dept Hematol, London, England
[4] Canc Res UK, London Res Inst, Haematopoiet Stem Cell Lab, London, England
来源：
LEUKEMIA | 2007年 / 21卷 / 03期
关键词：
D O I：
10.1038/sj.leu.2404514
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：550 / 551
页数：2
相关论文
共 50 条
  • [31] Simultaneous Detection of FLT3-ITD, FLT3-D835 and NPM1 Mutations in AML
    Bernardino, L. P.
    Nagy, P. L.
    Hensel, J. W.
    JOURNAL OF MOLECULAR DIAGNOSTICS, 2008, 10 (06): : 578 - 578
  • [32] Study of HOTAIR LncRNA in AML patients in context to FLT3-ITD and NPM1 mutations status
    Mona Salah
    Hamdy Zawam
    Neven Bahaa Fouad
    Nohair Soliman
    Fatma Abdel Wahab Abdel Maksoud
    Egyptian Journal of Medical Human Genetics, 22
  • [33] Study of HOTAIR LncRNA in AML patients in context to FLT3-ITD and NPM1 mutations status
    Salah, Mona
    Zawam, Hamdy
    Fouad, Neven Bahaa
    Soliman, Nohair
    Maksoud, Fatma Abdel Wahab Abdel
    EGYPTIAN JOURNAL OF MEDICAL HUMAN GENETICS, 2021, 22 (01)
  • [34] Impact of FLT3-ITD Mutations in Patients with Normal Karyotype Acute Myeloid Leukemia Undergoing Allogeneic Stem Cell Transplantation
    Grillo, Giovanni
    Zucchetti, Elisa
    Inzoli, Elena
    Mancini, Valentina
    Forno, Barbara
    Lotesoriere, Ivana
    Bertani, Giambattista
    Cairoli, Roberto
    BLOOD, 2017, 130
  • [35] TET2, ANPM1 and FLT3-ITD Gene Mutations in Normal Karyotype Acute Myeloid Leukemia
    Sun, Aining
    Tian, Xiaopeng
    Yin, Jia
    Li, Weiyang
    Chen, Suning
    Wu Depei
    BLOOD, 2012, 120 (21)
  • [36] Amount of bone marrow blasts is strongly correlated to NPM1 and FLT3-ITD mutation rate in AML with normal karyotype
    Haferlach, Torsten
    Bacher, Ulrike
    Alpermann, Tamara
    Haferlach, Claudia
    Kern, Wolfgang
    Schnittger, Susanne
    LEUKEMIA RESEARCH, 2012, 36 (01) : 51 - 58
  • [37] Prognostic Significance Of NPM1 mutations In The Absence Of FLT3-ITD in Older Patients With AML: A SWOG Report
    Ostronoff, Fabiana
    Othus, Megan
    Meshinchi, Soheil
    Godwin, John E.
    Kopecky, Kenneth J.
    List, Alan
    Oehler, Vivian G.
    Petersdorf, Stephen
    Pogosova-Agadjanyan, Era L.
    Radich, Jerald
    Willman, Cheryl L.
    Appelbaum, Frederick R.
    Stirewalt, Derek L.
    BLOOD, 2013, 122 (21)
  • [38] CD19/CD7 DUAL POSITIVE AML: A MARKER PROFILE ASSOCIATED WITH FLT3-ITD POSITIVE, NPM1-MUTATED NORMAL KARYOTYPE AML
    Vevai, X. J.
    O'Shea, K.
    Keane, S.
    Racevskis, J.
    Gallagher, R.
    Ketterling, R.
    Tallman, M. S.
    Wiernik, P. H.
    Paiettal, E.
    CYTOMETRY PART B-CLINICAL CYTOMETRY, 2009, 76B (06) : 406 - 406
  • [39] Patient-derived AML mouse models with FLT3-ITD and IDH1 mutations
    Kaur, P.
    Brehm, M.
    Greiner, D.
    Shultz, L.
    Cheng, M.
    Keck, J.
    Cai, D.
    EUROPEAN JOURNAL OF CANCER, 2016, 69 : S109 - S110
  • [40] Impact of FLT3-ITD diversity on response to induction chemotherapy in patients with acute myeloid leukemia
    Fischer, Mike
    Schnetzke, Ulf
    Spies-Weisshart, Baerbel
    Walther, Mario
    Fleischmann, Maximilian
    Hilgendorf, Inken
    Hochhaus, Andreas
    Scholl, Sebastian
    HAEMATOLOGICA, 2017, 102 (04) : E129 - E131
12345