Al2O3:C optically stimulated luminescence dosimeters (OSLDs) for ultra-high dose rate proton dosimetry

被引:44
|
作者
Christensen, Jeppe Brage [1 ]
Togno, Michele [2 ]
Nesteruk, Konrad Pawel [2 ]
Psoroulas, Serena [2 ]
Meer, David [2 ]
Weber, Damien Charles [2 ,3 ,4 ]
Lomax, Tony [2 ,5 ]
Yukihara, Eduardo G. [1 ]
Safai, Sairos [2 ]
机构
[1] Paul Scherrer Inst, Dept Radiat Safety & Secur, Villigen, Switzerland
[2] Paul Scherrer Inst, Ctr Proton Therapy, Villigen, Switzerland
[3] Univ Hosp Zurich, Dept Radiat Oncol, Zurich, Switzerland
[4] Univ Hosp Bern, Dept Radiat Oncol, Bern, Switzerland
[5] Swiss Fed Inst Technol, Dept Phys, Zurich, Switzerland
来源
PHYSICS IN MEDICINE AND BIOLOGY | 2021年 / 66卷 / 08期
基金
瑞士国家科学基金会;
关键词
FLASH; proton dosimetry; optically stimulated luminescence; Al2O3; C; ultra-high dose rate; RATE DEPENDENCE;
D O I
10.1088/1361-6560/abe554
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The response of Al2O3:C optically stimulated luminescence detectors (OSLDs) was investigated in a 250 MeV pencil proton beam. The OSLD response was mapped for a wide range of average dose rates up to 9000 Gy s(-1), corresponding to a similar to 150 kGy s(-1) instantaneous dose rate in each pulse. Two setups for ultra-high dose rate (FLASH) experiments are presented, which enable OSLDs or biological samples to be irradiated in either water-filled vials or cylinders. The OSLDs were found to be dose rate independent for all dose rates, with an average deviation <1% relative to the nominal dose for average dose rates of (1-1000) Gy s(-1) when irradiated in the two setups. A third setup for irradiations in a 9000 Gy s(-1) pencil beam is presented, where OSLDs are distributed in a 3 x 4 grid. Calculations of the signal averaging of the beam over the OSLDs were in agreement with the measured response at 9000 Gy s(-1). Furthermore, a new method was presented to extract the beam spot size of narrow pencil beams, which is in agreement within a standard deviation with results derived from radiochromic films. The Al2O3:C OSLDs were found applicable to support radiobiological experiments in proton beams at ultra-high dose rates.
引用
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页数:11
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