Four new highly oxidized sesquiterpene lactones from the leaves of Artemisia argyi

被引：8
|
作者：
Zhao, Hua-Rong
Liu, Xiao-Qin
Wu, Xiu-Tao
Kong, Ling-Yi [1 ,2 ]
Luo, Jian-Guang [1 ,2 ]
机构：
[1] China Pharmaceut Univ, Sch Tradit Chinese Pharm, Jiangsu Key Lab Bioact Nat Prod Res, 24 Tong Jia Xiang, Nanjing 210009, Peoples R China
[2] China Pharmaceut Univ, Sch Tradit Chinese Pharm, State Key Lab Nat Med, 24 Tong Jia Xiang, Nanjing 210009, Peoples R China
来源：
PHYTOCHEMISTRY LETTERS | 2021年 / 43卷
关键词：
Sesquiterpene lactones; Argyoxynolides; Artemisia argyi; Nitric oxide; DERIVATIVES; CONFIGURATION; MOXA;
D O I：
10.1016/j.phytol.2021.03.011
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Four new highly oxidized sesquiterpene lactones, Argyoxynolides A-D, along with two known analogs were isolated from the leaves of Artemisia argyi H.Le ' v. & Vaniot. Their structures were characterized utilizing extensive spectroscopic methods. All isolates were evaluated for the LPS-induced nitric oxide (NO) production inhibitory activity and one compound exhibited activity with IC50 = 37.95 +/- 4.39 mu M.
引用
收藏
页码：173 / 178
页数：6
相关论文
共 50 条
  • [21] SESQUITERPENE LACTONES FROM ARTEMISIA-HALOPHILA
    ARKHIPOVA, LI
    KASYMOV, SZ
    SIDYAKIN, GP
    KHIMIYA PRIRODNYKH SOEDINENII, 1970, (04): : 480 - +
  • [22] SESQUITERPENE LACTONES FROM ARTEMISIA-ARGENTEA
    ELEMARY, NA
    MAKBOUL, MA
    HAMED, M
    PHYTOCHEMISTRY, 1987, 26 (01) : 314 - 315
  • [23] SESQUITERPENE LACTONES FROM ARTEMISIA-ASSOANA
    MARCO, JA
    BARBERA, O
    MARTINEZ, V
    STRACK, D
    MEURER, B
    PLANTA MEDICA, 1988, (05) : 460 - 461
  • [24] SESQUITERPENE LACTONES FROM ARTEMISIA-RUTIFOLIA
    JAKUPOVIC, J
    TAN, RX
    BOHLMANN, F
    JIA, ZJ
    HUNECK, S
    PHYTOCHEMISTRY, 1991, 30 (05) : 1714 - 1716
  • [25] SESQUITERPENE LACTONES FROM ARTEMISIA-BARRELIERI
    MARCO, JA
    SANZ, JF
    YUSTE, A
    CARDA, M
    JAKUPOVIC, J
    PHYTOCHEMISTRY, 1991, 30 (11) : 3661 - 3668
  • [26] SESQUITERPENE LACTONES FROM IRANIAN ARTEMISIA SPECIES
    MARCO, JA
    SANZCERVERA, JF
    MANGLANO, E
    SANCENON, F
    RUSTAIYAN, A
    KARDAR, M
    PHYTOCHEMISTRY, 1993, 34 (06) : 1561 - 1564
  • [27] 2 SESQUITERPENE LACTONES FROM ARTEMISIA SPECIES
    NAGAKI, M
    PHYTOCHEMISTRY, 1984, 23 (02) : 462 - 464
  • [28] SESQUITERPENE LACTONES FROM ARTEMISIA-HISPANICA
    SANZ, JF
    BARBERA, O
    MARCO, JA
    PHYTOCHEMISTRY, 1989, 28 (08) : 2163 - 2167
  • [29] Sesquiterpene Lactones and Flavonoids from Artemisia albida
    E. M. Suleimenov
    F. M. Smagulova
    O. V. Morozova
    V. A. Raldugin
    I. Yu. Bagryanskaya
    Yu. V. Gatilov
    V. I. Yamovoi
    S. M. Adekenov
    Chemistry of Natural Compounds, 2005, 41 : 689 - 691
  • [30] SESQUITERPENE LACTONES FROM ARTEMISIA-RUTIFOLIA
    TAN, RX
    JIA, ZJ
    JAKUPOVIC, J
    BOHLMANN, F
    HUNECK, S
    PHYTOCHEMISTRY, 1991, 30 (09) : 3033 - 3035
12345