The interrelationship of PMY, GABA and GnRH in the sea lamprey, Petromyzon marinus

被引:0
|
作者
Mac Intyre, JK [1 ]
Chase, C [1 ]
Tobet, SA [1 ]
Sower, SA [1 ]
机构
[1] Univ New Hampshire, Dept Biochem, Durham, NH 03824 USA
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D O I
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中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The present study has determined that both PMY and GABA interact with the reproductive neuroendocrine axis of the sea lamprey, Lamprey GnRH-I and -III levels within the brain were elevated and circulating estradiol levels were suppressed in response to exogenous treatment of lamprey PMY in the female sea lamprey. Using an immunocytochemical procedure, GABA neurons were visualized in close proximity to developing GnRH neurons in the preoptic area/rostral hypothalamus, suggesting GABA may be influencing GnRH neuronal development similar to other vertebrates.
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页码:721 / 724
页数:4
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