Lyme neuroborreliosis (LNB) represents the second most frequent manifestation of Lyme disease (LD) in Europe after cutaneous involvement. In the USA, LNB represents the third most frequent manifestation of LD after cutaneous involvement and arthritis. The scope of this article is, in the light of recent publications, to review the specific manifestations of LNB in children including predictive models, and to discuss diagnosis criteria, new diagnostic tools and new therapeutic options. Differences in disease patterns between the USA and Europe are also highlighted.
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Med Univ Silesia, Students Sci Soc, Dept Pediat Neurol, Fac Med Sci Katowice, PL-40752 Katowice, PolandMed Univ Silesia, Students Sci Soc, Dept Pediat Neurol, Fac Med Sci Katowice, PL-40752 Katowice, Poland
Kozak, Sylwia
Kaminiow, Konrad
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Med Univ Silesia, Students Sci Soc, Dept Pediat Neurol, Fac Med Sci Katowice, PL-40752 Katowice, PolandMed Univ Silesia, Students Sci Soc, Dept Pediat Neurol, Fac Med Sci Katowice, PL-40752 Katowice, Poland
Kaminiow, Konrad
Kozak, Katarzyna
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Med Univ Silesia, Students Sci Soc, Dept Pediat Neurol, Fac Med Sci Katowice, PL-40752 Katowice, PolandMed Univ Silesia, Students Sci Soc, Dept Pediat Neurol, Fac Med Sci Katowice, PL-40752 Katowice, Poland
Kozak, Katarzyna
Paprocka, Justyna
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Med Univ Silesia, Dept Pediat Neurol, Fac Med Sci Katowice, PL-40752 Katowice, PolandMed Univ Silesia, Students Sci Soc, Dept Pediat Neurol, Fac Med Sci Katowice, PL-40752 Katowice, Poland
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Karolinska Univ Hosp, Astrid Lindgren Childrens Hosp, SE-17176 Stockholm, SwedenKarolinska Univ Hosp, Astrid Lindgren Childrens Hosp, SE-17176 Stockholm, Sweden
Bennet, R.
Lindgren, V.
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Karolinska Univ Hosp, Dept Clin Microbiol, SE-17176 Stockholm, SwedenKarolinska Univ Hosp, Astrid Lindgren Childrens Hosp, SE-17176 Stockholm, Sweden
Lindgren, V.
Wirgart, B. Zweygberg
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Karolinska Univ Hosp, Dept Clin Microbiol, SE-17176 Stockholm, SwedenKarolinska Univ Hosp, Astrid Lindgren Childrens Hosp, SE-17176 Stockholm, Sweden
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Gelre Hosp, Lyme Ctr Apeldoorn, POB 9014, NL-7300 Apeldoorn, NetherlandsGelre Hosp, Lyme Ctr Apeldoorn, POB 9014, NL-7300 Apeldoorn, Netherlands
Zomer, T. P.
Skogman, B. H.
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Uppsala Univ, Ctr Clin Res Dalarna, Falun, Sweden
Orebro Univ, Dept Med Sci, Orebro, SwedenGelre Hosp, Lyme Ctr Apeldoorn, POB 9014, NL-7300 Apeldoorn, Netherlands
Skogman, B. H.
Van Hensbroek, M. Boele
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Univ Amsterdam, Amsterdam Med Ctr, Dept Pediat, Amsterdam, NetherlandsGelre Hosp, Lyme Ctr Apeldoorn, POB 9014, NL-7300 Apeldoorn, Netherlands
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Overlook Med Ctr, Dept Neurosci, 99 Beauvoir Ave, Summit, NJ 07901 USA
Thomas Jefferson Univ, Sidney Kimmel Med Coll, Philadelphia, PA 19107 USAOverlook Med Ctr, Dept Neurosci, 99 Beauvoir Ave, Summit, NJ 07901 USA