Synthesis of Ugi-4CR boronate analogues via microwave irradiation

被引:2
|
作者
Hsiao, Chao-Yu [1 ]
Huang, Shi-Qing [1 ]
Lien, Wan-Hsing [1 ]
Hsu, Chen-Yun [1 ]
Hsieh, Kun-lin [1 ]
Lin, Meng-Hsuan [1 ]
Wu, Meng-Ju [1 ]
Fu, Chia-Chieh [1 ]
Chen, Hsien-Chi [1 ]
Fang, Hao-Ping [1 ]
Li, Chia-Jung [1 ]
Pan, Po-Shen [1 ]
机构
[1] Tamkang Univ, Dept Chem, 151 Yingzhuan Rd, New Taipei 25137, Taiwan
关键词
Boron; Multicomponent reaction; Ugi reaction; Suzuki-Miyaura cross-coupling; PEPTIDASE-4 INHIBITOR PHX1149; FACTOR-KAPPA-B; MULTICOMPONENT REACTIONS; PS-341;
D O I
10.1007/s11164-016-2433-y
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The synthetic condition for the synthesis of boronate ester Ugi-4CR analogs under mild conditions was developed. The reported reactions were carried out in methanol and promoted by microwave heating. This synthetic strategy could provide unique access to a broad range of boron-containing chemical libraries.
引用
收藏
页码:3585 / 3597
页数:13
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