Characterization of genomic alterations of cytarabine-resistant AML cells with FLT3-ITD mutation

被引:0
|
作者
Yen, J. H. [1 ]
Chen, Z. A. [2 ]
Lin, L. I. [3 ]
Chen, P. Y. [4 ]
机构
[1] Tzu Chi Univ, Dept Mol Biol & Human Genet, Hualien, Taiwan
[2] Tzu Chi Univ, Dept Life Sci, Hualien, Taiwan
[3] Natl Taiwan Univ, Dept Clin Lab Sci & Med Biotechnol, Taipei, Taiwan
[4] Hualien Tzu Chi Hosp, Ctr Med Genet, Hualien, Taiwan
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
P13.06B
引用
收藏
页码:1608 / 1608
页数:1
相关论文
共 50 条
  • [21] Molecular cytogenetic characterization of Polyploid Giant Cancer Cells (PGCCs) in cytarabine-resistant AML cells
    Chen, Pei-Yi
    Lin, Yu-Xuan
    Wu, Chia-Ling
    Yen, Jui-Hung
    EUROPEAN JOURNAL OF HUMAN GENETICS, 2024, 32 : 1251 - 1252
  • [22] Discovery of a highly selective FLT3 inhibitor with specific proliferation inhibition against AML cells harboring FLT3-ITD mutation
    Heng, Hao
    Zhi, Yanle
    Yuan, Haoliang
    Wang, Zhijie
    Li, Hongmei
    Wang, Shuxian
    Tian, Jieyi
    Liu, Haichun
    Chen, Yadong
    Lu, Tao
    Ran, Ting
    Lu, Shuai
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 163 : 195 - 206
  • [23] Role of Autophagy in Resistance of FLT3-ITD AML Stem Cells to FLT3 TKI Treatment
    Qiu, Shaowei
    Yan, Chengcheng
    Paterson, Andrew J.
    Li, Hui
    Anderson, Nick
    Abraham, Ajay
    He, Jianbo
    Shah, Mansi
    Agarwal, Puneet
    Yang, Jing
    Xie, Min
    Lu, Rui
    Welner, Rob S.
    Bhatia, Ravi
    BLOOD, 2019, 134
  • [24] Resistance to AC220 in FLT3-ITD+ AML is mediated by a secondary FLT3-ITD F691L mutation
    Albers, C.
    Leischner, H.
    Verbeek, M.
    Yu, C.
    von Bubnoff, N.
    Peschel, C.
    Duyster, J.
    ONKOLOGIE, 2012, 35 : 117 - 117
  • [25] Proteasome Inhibitors Induce FLT3-ITD Degradation through Autophagy in AML Cells
    Larrue, C.
    Saland, E.
    Boutzen, H.
    David, M.
    Joffre, C.
    Delabesse, E.
    Manenti, S.
    Sarry, J. E.
    Recher, C.
    ANNALS OF HEMATOLOGY, 2015, 94 (SUPPL 1) : 79 - 80
  • [26] Proteasome inhibitors induce FLT3-ITD degradation through autophagy in AML cells
    Larrue, Clement
    Saland, Estelle
    Boutzen, Helena
    Vergez, Francois
    David, Marion
    Joffre, Carine
    Hospital, Marie-Anne
    Tamburini, Jerome
    Delabesse, Eric
    Manenti, Stephane
    Sarry, Jean Emmanuel
    Recher, Christian
    BLOOD, 2016, 127 (07) : 882 - 892
  • [27] Proteasome Inhibitors Induce FLT3-ITD Degradation through Autophagy in AML Cells
    Larrue, C.
    Saland, E.
    Boutzen, H.
    David, M.
    Joffre, C.
    Delabesse, E.
    Manenti, S.
    Sarry, J. E.
    Recher, C.
    ANNALS OF HEMATOLOGY, 2015, 94 : S79 - S80
  • [28] Effective Combination of CPX-351 with FLT3 Inhibitors in AML Blasts Harboring the FLT3-ITD Mutation
    Edwards, David K.
    Javidi-Sharifi, Nathalie
    Rofelty, Angela
    Rosenfeld, Claire
    Roth-Carter, Riley
    Tardi, Paul
    Mayer, Lawrence
    Tyner, Jeffrey W.
    BLOOD, 2016, 128 (22)
  • [29] Uncovering the Genomic Landscape in Newly Diagnosed and Relapsed Pediatric Cytogenetically Normal FLT3-ITD AML
    Buelow, Daelynn R.
    Pounds, Stanley B.
    Wang, Yong-Dong
    Shi, Lei
    Li, Yongjin
    Finkelstein, David
    Shurtleff, Sheila
    Neale, Geoffrey
    Inaba, Hiroto
    Ribeiro, Raul C.
    Palumbo, Reid
    Garrison, Dominique
    Orwick, Shelley J.
    Blachly, James S.
    Kroll, Karl
    Byrd, John C.
    Gruber, Tanja A.
    Rubnitz, Jeffrey E.
    Baker, Sharyn D.
    CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2019, : 641 - 647
  • [30] FLT3-ITD activation mediates resistance to the BCL-2 selective antagonist, venetoclax, in FLT3-ITD mutant AML models
    Mali, Raghuveer
    Lasater, Elisabeth A.
    Doyle, Kelly
    Malla, Ritu
    Boghaert, Erwin
    Souers, Andrew
    Leverson, Joel
    Sampath, Deepak
    MOLECULAR CANCER THERAPEUTICS, 2018, 17 (01)