The many roles of microRNAs in brain tumor biology

被引：60

作者：

Turner, Jay D. ^{[1
]}

Williamson, Richard ^{[1
]}

Almefty, Kaith K. ^{[1
]}

Nakaji, Peter ^{[1
]}

Porter, Randall ^{[1
]}

Tse, Victor ^{[2
]}

Kalani, M. Yashar S. ^{[1
]}

机构：

[1] Barrow Neurol Inst, Div Neurosurg, Phoenix, AZ 85013 USA

[2] Permanente Med Grp Inc, Dept Neurosurg, Redwood City, CA USA

来源：

NEUROSURGICAL FOCUS | 2010年 / 28卷 / 01期

关键词：

microRNA; glioma; medulloblastoma; cancer stem cell; CANCER STEM-CELLS; CHRONIC LYMPHOCYTIC-LEUKEMIA; SONIC HEDGEHOG; HUMAN MEDULLOBLASTOMA; DOWN-REGULATION; OVARIAN-CANCER; GLIOMA-CELLS; IN-VIVO; EXPRESSION; GLIOBLASTOMA;

D O I：

10.3171/2009.10.FOCUS09207

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

MicroRNAs (miRNAs) are now recognized as the primary RNAs involved in the purposeful silencing of the cell's own message. In addition to the established role of miRNAs as developmental regulators of normal cellular function, they have recently been shown to be important players in pathological states such as cancer. The authors review the literature on the role of miRNAs in the formation and propagation of gliomas and medulloblastomas, highlighting the potential of these molecules and their inhibitors as therapeutics. (DOI: 10.3171/2009.10.FOCUS09207)

引用

页码：E3.1 / E3.7

页数：7

共 50 条

[21] Roles of heparan sulphate glycosaminoglycans in tumor biology
Sasisekharan, R
GLYCOBIOLOGY, 2002, 12 (10) : 642 - 642
[22] MESOTHELIOMA SPECIFIC MICRORNAS AS NOVEL BIOMARKERS AND REGULATORS OF TUMOR BIOLOGY
Badrian, B.
Birnie, K. A.
Lee, Y. C. G.
Creaney, J.
Robinson, B.
Musk, A. W.
Mutsaers, S. E.
RESPIROLOGY, 2012, 17 : 55 - 55
[23] Micro-masters of glioblastoma biology and therapy: increasingly recognized roles for microRNAs
Floyd, Desiree
Purow, Benjamin
NEURO-ONCOLOGY, 2014, 16 (05) : 622 - 627
[24] Biology of brain tumor stem cells
Sanai, Nader
Berger, Mitchel S.
NEUROSURGICAL FOCUS, 2008, 24 (3-4)
[25] BRAIN-TUMOR BIOLOGY AND THERAPY
VERTOSICK, FT
CURRENT OPINION IN NEUROLOGY AND NEUROSURGERY, 1991, 4 (01): : 24 - 28
[26] BASIS OF BRAIN-TUMOR BIOLOGY
KORNBLITH, PL
SURGICAL NEUROLOGY, 1995, 44 (01): : 54 - 54
[27] Emerging roles for Mitochondrial Rho GTPases in tumor biology
Boulton, Dillon P.
Caino, M. Cecilia
JOURNAL OF BIOLOGICAL CHEMISTRY, 2024, 300 (09)
[28] Roles of omental and bone marrow adipocytes in tumor biology
Cha, Yoon Jin
Koo, Ja Seung
ADIPOCYTE, 2019, 8 (01) : 304 - 317
[29] Analysis of microRNAs in cerebrospinal fluid of brain tumor patients
Sana, Jiri
Kopkova, Alena
Vecera, Marek
Juracek, Jaroslav
Machackova, Tana
Ahmad, Parwez
Gablo, Natalia Anna
Fadrus, Pavel
Svoboda, Marek
Slaby, Ondrej
CANCER RESEARCH, 2018, 78 (13)
[30] The Many Roles of the Rock: A Qualitative Inquiry into the Roles and Responsibilities of Fathers of Children with Brain Tumors
Robinson, Jacob E.
Huskey, David
Schwartz, Jonathan
Weaver, Meaghann S.
CHILDREN-BASEL, 2019, 6 (10):

← 1 2 3 4 5 →