ANTIBIOTIC RESISTANCE OF MICROORGANISMS ISOLATED FROM MILK

The performed literature analysis has shown that the resistance of microorganisms to antibacterial drugs remains a global problem all over the world. It has been established that in the etiological structure of mastitis of cows in cattle farms of Ukraine prevail Staphylococcus spp. (45.0 %), Streptococcus spp. (29.3 %) and Escherichia coli (17.8 %). The causative agents of staphylococcal etiology have pathogenicity factors, namely, plasmocoagulase (55.8 %), lecithinase (75.6 %) and hemolysins (79.1 %); resistance to Benzylpenicillinum (55.8 %), Oxacillin (30.3 %), Tetracyclin (89.6 %), Azithromycin (63.9 %), Erythromycin (55.8 %). E..oli and Streptococcus spp. has the highest (p=0.0001; p=0.0008) resistance to Tetracyclin (73.5 %, 58.9 %), Cefazolin (64.7 %, 37.5 %) and Doxycycline (58.8 %, 53.6 %), the smallest (p=0.0001; p=0.0008) to fluoroquinolones.