Synthesis of stereoisomeric 4-(2-methylindolin-1-yl)and 4-(2-methylindol-1-yl) derivatives of glutamic acid

被引：4

作者：

Krasnov, VP ^{[1
]}

Vigorov, AY ^{[1
]}

Nizova, IA ^{[1
]}

Grishakov, AN ^{[1
]}

Evstigneeva, NG ^{[1
]}

Kodess, MI ^{[1
]}

机构：

[1] Russian Acad Sci, Ural Branch, IYa Postovsky Inst Organ Synth, Ekaterinburg 620219, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 2004年 / 53卷 / 06期

基金：

俄罗斯基础研究基金会;

关键词：

glutamic acid; 2-methylindoline; 2-methylindole; nucleophilic substitution; stereoisomers;

D O I：

10.1023/B:RUCB.0000042295.70355.47

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reaction of dimethyl (2S,4RS)-N-phthaloyl-4-bromoglutamate with 2-methylindoline afforded diastereomeric 4-(2 -methylindolin-1-yl)-(S)-glutamic acid derivatives, whose oxidation gave rise to 4-(2-methylindol-1-yl)-(S)-glutamic acid derivatives.

引用

页码：1327 / 1330

页数：4

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