Rapid continuous photoflow synthesis of naturally occurring arylnaphthalene lignans and their analogs

被引:3
|
作者
Ge, Xiang [1 ]
Jiang, Haowen [2 ]
Li, Jinlong [1 ]
机构
[1] Nantong Univ, Sch Pharm, Nantong, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai, Peoples R China
基金
中国国家自然科学基金;
关键词
Arylnaphthalene lignans; continuous photoflow synthesis; intramolecular Diels– Alder reaction;
D O I
10.1080/14786419.2021.1920019
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Naturally occurring arylnaphthalene lignans (ANLs) are subclass of lignans in many dietary or medicinal plants. The progressing interest of ANLs is due to their diversified biological activities. Herein, we developed a convenient method for the preparation of naturally occurring ANLs and their analogs through the continuous photoflow intramolecular Diels-Alder reaction in several minutes under mild conditions with good yields and regioselectivities.
引用
收藏
页码:5086 / 5090
页数:5
相关论文
共 50 条
  • [31] SYNTHESIS OF 1-OXA ANALOGS OF NATURALLY-OCCURRING CEPHALOSPORINS AND CEPHAMYCINS
    SENDO, Y
    KONOIKE, T
    MURAKAMI, M
    YOSHIOKA, M
    HETEROCYCLES, 1981, 16 (04) : 599 - 603
  • [32] SYNTHESIS OF 5'-PHOSPHATES OF NATURALLY OCCURRING 6-UREIDOPURINE RIBONUCLEOSIDES AND THEIR ANALOGS
    HONG, CI
    CHHEDA, GB
    JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (08) : 956 - 959
  • [33] Synthesis and In Vitro Anticancer Activity of Triazolyl Analogs of Podophyllotoxin, a Naturally Occurring Lignin
    B. A. Ganaie
    J. A. Banday
    B. A. Bhat
    T. Ara
    Russian Journal of Organic Chemistry, 2021, 57 : 2039 - 2047
  • [34] SYNTHESIS OF NATURALLY-OCCURRING PONGAGALLONE-A, PONGAGALLONE-B AND THEIR ANALOGS
    JAIN, AC
    PRASAD, AK
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1989, 28 (02): : 193 - 194
  • [35] A new benzannulation reaction and its application in the multiple parallel synthesis of arylnaphthalene lignans
    Flanagan, SR
    Harrowven, DC
    Bradley, M
    TETRAHEDRON, 2002, 58 (30) : 5989 - 6001
  • [36] Transpositive Tandem Annulation of Phthalides with Allene Carboxylates: Regioselective Synthesis of Arylnaphthalene Lignans
    Mal, Dipakranjan
    Jana, Supriti
    JOURNAL OF ORGANIC CHEMISTRY, 2016, 81 (23): : 11857 - 11865
  • [37] Synthesis and hypolipidemic activity of diesters of arylnaphthalene lignan and their heteroaromatic analogs
    Kuroda, T
    Kondo, K
    Iwasaki, T
    Ohtani, A
    Takashima, K
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1997, 45 (04) : 678 - 684
  • [38] SYNTHESIS OF OPTICALLY PURE GOMISI LIGNANS - THE TOTAL SYNTHESIS OF (+)-SCHIZANDRIN, (+)-GOMISIN-A, AND (+)-ISOSCHIZANDRIN IN NATURALLY-OCCURRING FORMS
    TANAKA, M
    MUKAIYAMA, C
    MITSUHASHI, H
    MARUNO, M
    WAKAMATSU, T
    JOURNAL OF ORGANIC CHEMISTRY, 1995, 60 (14): : 4339 - 4352
  • [39] Naturally occurring lignans efficiently induce apoptosis in colorectal tumor cells
    Hausott, B
    Greger, H
    Marian, B
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2003, 129 (10) : 569 - 576
  • [40] Naturally occurring lignans efficiently induce apoptosis in colorectal tumor cells
    B. Hausott
    H. Greger
    B. Marian
    Journal of Cancer Research and Clinical Oncology, 2003, 129 : 569 - 576