Rapid continuous photoflow synthesis of naturally occurring arylnaphthalene lignans and their analogs

被引:3
|
作者
Ge, Xiang [1 ]
Jiang, Haowen [2 ]
Li, Jinlong [1 ]
机构
[1] Nantong Univ, Sch Pharm, Nantong, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai, Peoples R China
基金
中国国家自然科学基金;
关键词
Arylnaphthalene lignans; continuous photoflow synthesis; intramolecular Diels– Alder reaction;
D O I
10.1080/14786419.2021.1920019
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Naturally occurring arylnaphthalene lignans (ANLs) are subclass of lignans in many dietary or medicinal plants. The progressing interest of ANLs is due to their diversified biological activities. Herein, we developed a convenient method for the preparation of naturally occurring ANLs and their analogs through the continuous photoflow intramolecular Diels-Alder reaction in several minutes under mild conditions with good yields and regioselectivities.
引用
收藏
页码:5086 / 5090
页数:5
相关论文
共 50 条
  • [1] Synthesis of arylnaphthalene lignans
    Chirisa, Shingiria
    Feld, William A.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 231
  • [2] Facile synthesis of naturally occurring nor-lignans (±)-Machicendiol and its analogs
    More, Kishor R.
    Mali, R. S.
    SYNTHETIC COMMUNICATIONS, 2017, 47 (08) : 788 - 792
  • [3] AN EFFICIENT SYNTHESIS OF HETEROCYCLIC-ANALOGS OF 1-ARYLNAPHTHALENE LIGNANS
    KURODA, T
    TAKAHASHI, M
    OGIKU, T
    OHMIZU, H
    NISHITANI, T
    KONDO, K
    IWASAKI, T
    JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (24): : 7353 - 7357
  • [4] SYNTHESIS OF 2 ARYLNAPHTHALENE LIGNANS
    GONZALEZ, AG
    PEREZ, JP
    TRUJILLO, JM
    TETRAHEDRON, 1978, 34 (07) : 1011 - 1013
  • [5] ARYLNAPHTHALENE LIGNANS - SYNTHESIS OF HELIOXANTHIN
    HOLMES, TL
    STEVENSO.R
    JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1971, (11): : 2091 - &
  • [6] THE NATURALLY OCCURRING LIGNANS
    HEARON, WM
    MACGREGOR, WS
    CHEMICAL REVIEWS, 1955, 55 (05) : 957 - 1068
  • [7] Design, synthesis, and evaluation of cytotoxic activities of arylnaphthalene lignans and aza-analogs
    Ourhzif, El-Mahdi
    Paris, Arnaud
    Abrunhosa-Thomas, Isabelle
    Ketatni, El Mostafa
    Chalard, Pierre
    Khouili, Mostafa
    Daniellou, Richard
    Troin, Yves
    Akssira, Mohamed
    ARCHIV DER PHARMAZIE, 2021, 354 (06)
  • [8] The synthesis of naturally occurring peptides and their analogs
    Cupido, Tommaso
    Tulla-Puche, Judit
    Spengler, Jan
    Albericio, Fernando
    CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT, 2007, 10 (06) : 768 - 783
  • [9] SYNTHESIS OF (+/-)-DENDROTRIFIDIOL AND ITS NATURALLY OCCURRING ANALOGS
    KOBAYASHI, A
    TAMAGAWA, K
    YAMASHITA, K
    AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1977, 41 (04): : 691 - 695
  • [10] Cardiovascular activity of naturally occurring lignans
    Ghisalberti, EL
    PHYTOMEDICINE, 1997, 4 (02) : 151 - 166