An autopsy case of Alzheimer's disease with a progressive supranuclear palsy overlap

被引：6
|
作者：
Urasaki, K
Kuriki, K
Namerikawa, M
Satoh, S
Ikeguchi, K
Fukayama, M
Saito, K
Nakano, I
机构：
[1] Jichi Med Sch, Omiya Med Ctr, Dept Pathol, Omiya, Saitama 3300834, Japan
[2] Jichi Med Sch, Dept Neurol, Omiya, Saitama 3300834, Japan
来源：
NEUROPATHOLOGY | 2000年 / 20卷 / 03期
关键词：
Alzheimer's disease; neurofibrillary tangle; progressive supranuclear palsy; senile plaque; tau-positive abnormal structures;
D O I：
10.1046/j.1440-1789.2000.00334.x
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
A 74-year-old man developed abnormal forgetfulness, soon followed by unstable speech content and marked disorientation. At 77 years of age, the patient started to occasionally fall, an aspect of progressive supranuclear palsy. He then became bedridden. The patient eventually died of pneumonia at 79 years of age. Neuropathological examination revealed profiles of both progressive supranuclear palsy and Alzheimer's disease. Although the two conditions both belong to tauopathy, their pathologically proven combination was rare. Furthermore, the case had the possibility of being a subgroup of tauopathy.
引用
收藏
页码：233 / 238
页数：6
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