Identification of functional domains of the ATP-gated P2x2 receptor using silver and scanning cysteine mutagenesis.

被引:0
|
作者
Haines, W [1 ]
Voigt, M [1 ]
Egan, T [1 ]
机构
[1] St Louis Univ, Hlth Sci Ctr, Dept Pharmacol & Physiol Sci, St Louis, MO 63104 USA
关键词
D O I
暂无
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
引用
收藏
页码:A316 / A316
页数:1
相关论文
共 50 条
  • [31] Role of an intracellular cysteine residue in the responsiveness of P2X2 receptor/channel to ATP
    Ojima, H
    Nakazawa, K
    Ishii-Nozawa, R
    Takeuchi, K
    Ohno, Y
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2004, 94 : 193P - 193P
  • [32] ATP Binding Site Mutagenesis Reveals Different Subunit Stoichiometry of Functional P2X2/3 and P2X2/6 Receptors
    Hausmann, Ralf
    Bodnar, Mandy
    Woltersdorf, Ronja
    Wang, Haihong
    Fuchs, Martin
    Messemer, Nanette
    Qin, Ying
    Guenther, Janka
    Riedel, Thomas
    Grohmann, Marcus
    Nieber, Karen
    Schmalzing, Guenther
    Rubini, Patrizia
    Illes, Peter
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (17) : 13930 - 13943
  • [33] Molecular properties of ATP-gated P2X receptor ion channels
    Vial, C
    Roberts, JA
    Evans, RJ
    TRENDS IN PHARMACOLOGICAL SCIENCES, 2004, 25 (09) : 487 - 493
  • [34] Polar residues of TMD2 influence ionic permeability of recombinant ATP-gated P2X2 receptors.
    Migita, K
    Haines, W
    Voigt, M
    Egan, TM
    BIOPHYSICAL JOURNAL, 2001, 80 (01) : 104A - 104A
  • [35] Rectification of ATP-gated current of rat P2X2 and P2X7 receptors depends on the cytoplasmic N-terminus
    Migita, Keisuke
    Oyabu, Kohei
    Terada, Kazuki
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2023, 688
  • [36] Dynamic aspects of functional regulation of the ATP receptor channel P2X2
    Kubo, Yoshihiro
    Fujiwara, Yuichiro
    Keceli, Batu
    Nakajo, Koichi
    JOURNAL OF PHYSIOLOGY-LONDON, 2009, 587 (22): : 5317 - 5324
  • [37] Voltage-clamp fluorometry analysis of structural rearrangements of ATP-gated channel P2X2 upon hyperpolarization
    Andriani, Rizki Tsari
    Kubo, Yoshihiro
    ELIFE, 2021, 10
  • [38] Expression of the P2X(2) receptor subunit of the ATP-gated ion channel in the retina
    Greenwood, D
    Yao, WP
    Housley, GD
    NEUROREPORT, 1997, 8 (05) : 1083 - 1088
  • [39] Two mechanisms for inward rectification of current flow through the purinoceptor P2X2 class of ATP-gated channels
    Zhou, Z
    Hume, RI
    JOURNAL OF PHYSIOLOGY-LONDON, 1998, 507 (02): : 353 - 364
  • [40] Molecular cloning and functional characterization of the zebrafish ATP-gated ionotropic receptor P2X3 subunit
    Egan, TM
    Cox, JA
    Voigt, MM
    FEBS LETTERS, 2000, 475 (03) : 287 - 290