Effect of rhubarb on extravascular lung water in patients with acute respiratory distress syndrome

被引：10
|
作者：
He, Jianxin [1 ]
Si, Xiaoshui [1 ]
Ji, Mingxia [1 ]
Huang, Jing [1 ]
Zheng, Wenjuan [1 ]
Wang, Jiao [1 ]
Wang, Junfeng [1 ]
Zhu, Lijun [1 ]
机构：
[1] Yiwu Cent Hosp, Crit Care Med, 699 Jiangdong Rd, Yiwu 322000, Zhejiang, Peoples R China
来源：
REVISTA DA ASSOCIACAO MEDICA BRASILEIRA | 2017年 / 63卷 / 05期
关键词：
rhubarb; ARDS; EVLWI; oxygenation index; MULTIPLE ORGAN FAILURE; SURVIVAL;
D O I：
10.1590/1806-9282.63.05.435
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Objective: The aim of this study was to evaluate the effect of rhubarb on extravascular lung water (EVLW) in patients with acute respiratory distress syndrome (ARDS). Method: A total of 80 patients with ARDS were randomly divided into a treatment group (40 cases) and control group (40 cases). Patients in the treatment group received rhubarb (30.0 g/d) and patients in the control group received conventional therapy for seven consecutive days. Extravascular lung water index (EVLWI) and pulmonary vascular permeability index (PVPI) were determined using pulse contour cardiac output (PiCCO) technology, and the oxygenation index was measured by blood gas analysis at baseline and on days 3, 5 and 7 after treatment. Results: The oxygenation index was higher and the levels of EVLWI and PVPI were lower after treatment in the two groups; however, these indexes showed significant differences on the 5th and 7th days after rhubarb treatment compared with the results in the control group (p<0.05). Conclusion: Rhubarb can decrease EVLWI and PVPI, and improve oxygenation in patients with ARDS.
引用
收藏
页码：435 / 440
页数：6
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